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| Thu Apr 7 | Time | Location |
|---|---|---|
| Milwaukee @ Chi Cubs | 2:20 PM | Wrigley Field |
| Cleveland @ Kansas City | 4:10 PM | Kauffman Stadium |
| Pittsburgh @ St. Louis | 4:15 PM | Busch Stadium |
| NY Mets @ Washington | 7:05 PM | Nationals Park |
| Cincinnati @ Atlanta | 8:08 PM | Truist Park |
| Houston @ LA Angels | 9:38 PM | Angel Stadium |
| San Diego @ Arizona | 9:40 PM | Chase Field |
| Fri Apr 8 | Time | Location |
| Boston @ NY Yankees | 1:05 PM | Yankee Stadium |
| Chi Sox @ Detroit | 1:10 PM | Comerica Park |
| Oakland @ Philadelphia | 3:05 PM | Citizens Bank Park |
| Baltimore @ Tampa Bay | 3:10 PM | Tropicana Field |
| Seattle @ Minnesota | 4:10 PM | Target Field |
| LA Dodgers @ Colorado | 4:10 PM | Coors Field |
| Miami @ SF Giants | 4:35 PM | Oracle Park |
| NY Mets @ Washington | 7:05 PM | Nationals Park |
| Texas @ Toronto | 7:07 PM | Rogers Centre |
| Cincinnati @ Atlanta | 7:20 PM | Truist Park |
| Houston @ LA Angels | 9:38 PM | Angel Stadium |
| San Diego @ Arizona | 9:40 PM | Chase Field |
| Sat Apr 9 | Time | Location |
| Baltimore @ Tampa Bay | 1:10 PM | Tropicana Field |
| Chi Sox @ Detroit | 1:10 PM | Comerica Park |
| Seattle @ Minnesota | 2:10 PM | Target Field |
| Pittsburgh @ St. Louis | 2:15 PM | Busch Stadium |
| Milwaukee @ Chi Cubs | 2:20 PM | Wrigley Field |
| Texas @ Toronto | 3:07 PM | Rogers Centre |
| Oakland @ Philadelphia | 4:05 PM | Citizens Bank Park |
| Miami @ SF Giants | 4:05 PM | Oracle Park |
| Boston @ NY Yankees | 4:05 PM | Yankee Stadium |
| Cleveland @ Kansas City | 4:10 PM | Kauffman Stadium |
| NY Mets @ Washington | 7:05 PM | Nationals Park |
| Cincinnati @ Atlanta | 7:20 PM | Truist Park |
| LA Dodgers @ Colorado | 8:10 PM | Coors Field |
| San Diego @ Arizona | 8:10 PM | Chase Field |
| Houston @ LA Angels | 9:07 PM | Angel Stadium |
| Sun Apr 10 | Time | Location |
| Oakland @ Philadelphia | 1:05 PM | Citizens Bank Park |
| Baltimore @ Tampa Bay | 1:10 PM | Tropicana Field |
| Chi Sox @ Detroit | 1:10 PM | Comerica Park |
| Cincinnati @ Atlanta | 1:35 PM | Truist Park |
| NY Mets @ Washington | 1:35 PM | Nationals Park |
| Texas @ Toronto | 1:37 PM | Rogers Centre |
| Cleveland @ Kansas City | 2:10 PM | Kauffman Stadium |
| Seattle @ Minnesota | 2:10 PM | Target Field |
| Pittsburgh @ St. Louis | 2:15 PM | Busch Stadium |
| Milwaukee @ Chi Cubs | 2:20 PM | Wrigley Field |
| LA Dodgers @ Colorado | 3:10 PM | Coors Field |
| Miami @ SF Giants | 4:05 PM | Oracle Park |
| Houston @ LA Angels | 4:07 PM | Angel Stadium |
| San Diego @ Arizona | 4:10 PM | Chase Field |
| Boston @ NY Yankees | 7:08 PM | Yankee Stadium |
| Mon Apr 11 | Time | Location |
| Cleveland @ Kansas City | 2:10 PM | Kauffman Stadium |
| Milwaukee @ Baltimore | 3:05 PM | Oriole Park at Camden Yards |
| Colorado @ Texas | 4:05 PM | Globe Life Field |
| Boston @ Detroit | 5:10 PM | Comerica Park |
| Oakland @ Tampa Bay | 6:40 PM | Tropicana Field |
| NY Mets @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Toronto @ NY Yankees | 7:05 PM | Yankee Stadium |
| Washington @ Atlanta | 7:20 PM | Truist Park |
| Seattle @ Minnesota | 7:40 PM | Target Field |
| Miami @ LA Angels | 9:38 PM | Angel Stadium |
| San Diego @ SF Giants | 9:45 PM | Oracle Park |
| Tue Apr 12 | Time | Location |
| Boston @ Detroit | 1:10 PM | Comerica Park |
| Cleveland @ Cincinnati | 4:10 PM | Great American Ball Park |
| Seattle @ Chi Sox | 4:10 PM | Guaranteed Rate Field |
| Chi Cubs @ Pittsburgh | 4:12 PM | PNC Park |
| Oakland @ Tampa Bay | 6:40 PM | Tropicana Field |
| NY Mets @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Toronto @ NY Yankees | 7:05 PM | Yankee Stadium |
| Milwaukee @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Miami @ LA Angels | 7:07 PM | Angel Stadium |
| Washington @ Atlanta | 7:20 PM | Truist Park |
| LA Dodgers @ Minnesota | 7:40 PM | Target Field |
| Kansas City @ St. Louis | 7:45 PM | Busch Stadium |
| Colorado @ Texas | 8:05 PM | Globe Life Field |
| Houston @ Arizona | 9:40 PM | Chase Field |
| San Diego @ SF Giants | 9:45 PM | Oracle Park |
| Wed Apr 13 | Time | Location |
| Washington @ Atlanta | 12:20 PM | Truist Park |
| Chi Cubs @ Pittsburgh | 12:35 PM | PNC Park |
| Cleveland @ Cincinnati | 12:35 PM | Great American Ball Park |
| NY Mets @ Philadelphia | 1:05 PM | Citizens Bank Park |
| Boston @ Detroit | 1:10 PM | Comerica Park |
| LA Dodgers @ Minnesota | 1:10 PM | Target Field |
| Houston @ Arizona | 3:40 PM | Chase Field |
| San Diego @ SF Giants | 3:45 PM | Oracle Park |
| Oakland @ Tampa Bay | 6:40 PM | Tropicana Field |
| Toronto @ NY Yankees | 7:05 PM | Yankee Stadium |
| Milwaukee @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Seattle @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| Thu Apr 14 | Time | Location |
| Oakland @ Tampa Bay | 1:10 PM | Tropicana Field |
| Seattle @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| St. Louis @ Milwaukee | 5:14 PM | American Family Field |
| Washington @ Pittsburgh | 6:35 PM | PNC Park |
| Philadelphia @ Miami | 6:40 PM | loanDepot Park |
| Toronto @ NY Yankees | 7:05 PM | Yankee Stadium |
| LA Angels @ Texas | 8:05 PM | Globe Life Field |
| Atlanta @ San Diego | 8:10 PM | Petco Park |
| Detroit @ Kansas City | 8:10 PM | Kauffman Stadium |
| Chi Cubs @ Colorado | 8:40 PM | Coors Field |
| Cincinnati @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Fri Apr 15 | Time | Location |
| Arizona @ NY Mets | 1:10 PM | Citi Field |
| Minnesota @ Boston | 2:10 PM | Fenway Park |
| Washington @ Pittsburgh | 6:35 PM | PNC Park |
| Philadelphia @ Miami | 6:40 PM | loanDepot Park |
| NY Yankees @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Oakland @ Toronto | 7:07 PM | Rogers Centre |
| SF Giants @ Cleveland | 7:10 PM | Progressive Field |
| Tampa Bay @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| LA Angels @ Texas | 8:05 PM | Globe Life Field |
| St. Louis @ Milwaukee | 8:10 PM | American Family Field |
| Detroit @ Kansas City | 8:10 PM | Kauffman Stadium |
| Chi Cubs @ Colorado | 8:40 PM | Coors Field |
| Atlanta @ San Diego | 9:40 PM | Petco Park |
| Houston @ Seattle | 9:42 PM | T-Mobile Park |
| Cincinnati @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sat Apr 16 | Time | Location |
| Arizona @ NY Mets | 1:10 PM | Citi Field |
| Tampa Bay @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Oakland @ Toronto | 3:07 PM | Rogers Centre |
| Atlanta @ San Diego | 4:05 PM | Petco Park |
| Minnesota @ Boston | 4:10 PM | Fenway Park |
| Detroit @ Kansas City | 4:10 PM | Kauffman Stadium |
| SF Giants @ Cleveland | 6:10 PM | Progressive Field |
| Philadelphia @ Miami | 6:10 PM | loanDepot Park |
| Washington @ Pittsburgh | 6:35 PM | PNC Park |
| LA Angels @ Texas | 7:05 PM | Globe Life Field |
| NY Yankees @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| St. Louis @ Milwaukee | 7:10 PM | American Family Field |
| Chi Cubs @ Colorado | 8:10 PM | Coors Field |
| Houston @ Seattle | 9:10 PM | T-Mobile Park |
| Cincinnati @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sun Apr 17 | Time | Location |
| NY Yankees @ Baltimore | 1:05 PM | Oriole Park at Camden Yards |
| Minnesota @ Boston | 1:35 PM | Fenway Park |
| Washington @ Pittsburgh | 1:35 PM | PNC Park |
| Oakland @ Toronto | 1:37 PM | Rogers Centre |
| Arizona @ NY Mets | 1:40 PM | Citi Field |
| SF Giants @ Cleveland | 1:40 PM | Progressive Field |
| Philadelphia @ Miami | 1:40 PM | loanDepot Park |
| St. Louis @ Milwaukee | 2:10 PM | American Family Field |
| Tampa Bay @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| LA Angels @ Texas | 2:35 PM | Globe Life Field |
| Chi Cubs @ Colorado | 3:10 PM | Coors Field |
| Cincinnati @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Houston @ Seattle | 4:10 PM | T-Mobile Park |
| Atlanta @ San Diego | 7:08 PM | Petco Park |
| Mon Apr 18 | Time | Location |
| Minnesota @ Boston | 11:10 AM | Fenway Park |
| Tampa Bay @ Chi Cubs | 7:40 PM | Wrigley Field |
| Pittsburgh @ Milwaukee | 7:40 PM | American Family Field |
| LA Angels @ Houston | 8:10 PM | Minute Maid Park |
| Philadelphia @ Colorado | 8:40 PM | Coors Field |
| Baltimore @ Oakland | 9:40 PM | RingCentral Coliseum |
| Cincinnati @ San Diego | 9:40 PM | Petco Park |
| Atlanta @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Tue Apr 19 | Time | Location |
| Arizona @ Washington | 1:05 PM | Nationals Park |
| SF Giants @ NY Mets | 3:10 PM | Citi Field |
| SF Giants @ NY Mets | 6:10 PM | Citi Field |
| NY Yankees @ Detroit | 6:40 PM | Comerica Park |
| St. Louis @ Miami | 6:40 PM | loanDepot Park |
| Arizona @ Washington | 7:05 PM | Nationals Park |
| Toronto @ Boston | 7:10 PM | Fenway Park |
| Tampa Bay @ Chi Cubs | 7:40 PM | Wrigley Field |
| Pittsburgh @ Milwaukee | 7:40 PM | American Family Field |
| LA Angels @ Houston | 8:10 PM | Minute Maid Park |
| Minnesota @ Kansas City | 8:10 PM | Kauffman Stadium |
| Philadelphia @ Colorado | 8:40 PM | Coors Field |
| Texas @ Seattle | 9:40 PM | T-Mobile Park |
| Baltimore @ Oakland | 9:40 PM | RingCentral Coliseum |
| Cincinnati @ San Diego | 9:40 PM | Petco Park |
| Atlanta @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed Apr 20 | Time | Location |
| Pittsburgh @ Milwaukee | 1:40 PM | American Family Field |
| Chi Sox @ Cleveland | 2:10 PM | Progressive Field |
| Philadelphia @ Colorado | 3:10 PM | Coors Field |
| Atlanta @ LA Dodgers | 3:10 PM | Dodger Stadium |
| Cincinnati @ San Diego | 4:10 PM | Petco Park |
| Chi Sox @ Cleveland | 5:10 PM | Progressive Field |
| Baltimore @ Oakland | 6:07 PM | RingCentral Coliseum |
| Tampa Bay @ Chi Cubs | 6:30 PM | Wrigley Field |
| NY Yankees @ Detroit | 6:40 PM | Comerica Park |
| LA Angels @ Houston | 6:40 PM | Minute Maid Park |
| St. Louis @ Miami | 6:40 PM | loanDepot Park |
| Arizona @ Washington | 7:05 PM | Nationals Park |
| SF Giants @ NY Mets | 7:10 PM | Citi Field |
| Toronto @ Boston | 7:10 PM | Fenway Park |
| Minnesota @ Kansas City | 8:10 PM | Kauffman Stadium |
| Texas @ Seattle | 9:40 PM | T-Mobile Park |
| Thu Apr 21 | Time | Location |
| SF Giants @ NY Mets | 1:10 PM | Citi Field |
| Chi Sox @ Cleveland | 1:10 PM | Progressive Field |
| NY Yankees @ Detroit | 1:10 PM | Comerica Park |
| Toronto @ Boston | 1:35 PM | Fenway Park |
| Minnesota @ Kansas City | 2:10 PM | Kauffman Stadium |
| Baltimore @ Oakland | 3:37 PM | RingCentral Coliseum |
| Arizona @ Washington | 4:05 PM | Nationals Park |
| St. Louis @ Miami | 6:40 PM | loanDepot Park |
| Pittsburgh @ Chi Cubs | 7:40 PM | Wrigley Field |
| Texas @ Seattle | 9:40 PM | T-Mobile Park |
| Fri Apr 22 | Time | Location |
| St. Louis @ Cincinnati | 6:40 PM | Great American Ball Park |
| SF Giants @ Washington | 7:05 PM | Nationals Park |
| Cleveland @ NY Yankees | 7:05 PM | Yankee Stadium |
| Milwaukee @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Boston @ Tampa Bay | 7:10 PM | Tropicana Field |
| Miami @ Atlanta | 7:20 PM | Truist Park |
| Pittsburgh @ Chi Cubs | 8:05 PM | Wrigley Field |
| Toronto @ Houston | 8:10 PM | Minute Maid Park |
| Chi Sox @ Minnesota | 8:10 PM | Target Field |
| Baltimore @ LA Angels | 9:38 PM | Angel Stadium |
| Texas @ Oakland | 9:40 PM | RingCentral Coliseum |
| NY Mets @ Arizona | 9:40 PM | Chase Field |
| LA Dodgers @ San Diego | 9:40 PM | Petco Park |
| Kansas City @ Seattle | 9:40 PM | T-Mobile Park |
| Sat Apr 23 | Time | Location |
| SF Giants @ Washington | 1:05 PM | Nationals Park |
| Cleveland @ NY Yankees | 1:05 PM | Yankee Stadium |
| Colorado @ Detroit | 1:10 PM | Comerica Park |
| Pittsburgh @ Chi Cubs | 2:20 PM | Wrigley Field |
| Chi Sox @ Minnesota | 4:05 PM | Target Field |
| Milwaukee @ Philadelphia | 4:05 PM | Citizens Bank Park |
| Texas @ Oakland | 4:07 PM | RingCentral Coliseum |
| Toronto @ Houston | 4:10 PM | Minute Maid Park |
| St. Louis @ Cincinnati | 4:10 PM | Great American Ball Park |
| Boston @ Tampa Bay | 6:10 PM | Tropicana Field |
| Colorado @ Detroit | 6:40 PM | Comerica Park |
| Miami @ Atlanta | 7:20 PM | Truist Park |
| NY Mets @ Arizona | 8:10 PM | Chase Field |
| LA Dodgers @ San Diego | 8:40 PM | Petco Park |
| Baltimore @ LA Angels | 9:07 PM | Angel Stadium |
| Kansas City @ Seattle | 9:10 PM | T-Mobile Park |
| Sun Apr 24 | Time | Location |
| Colorado @ Detroit | 1:10 PM | Comerica Park |
| Boston @ Tampa Bay | 1:10 PM | Tropicana Field |
| SF Giants @ Washington | 1:35 PM | Nationals Park |
| Miami @ Atlanta | 1:35 PM | Truist Park |
| Cleveland @ NY Yankees | 1:35 PM | Yankee Stadium |
| St. Louis @ Cincinnati | 1:40 PM | Great American Ball Park |
| Toronto @ Houston | 2:10 PM | Minute Maid Park |
| Chi Sox @ Minnesota | 2:10 PM | Target Field |
| Pittsburgh @ Chi Cubs | 2:20 PM | Wrigley Field |
| Baltimore @ LA Angels | 4:07 PM | Angel Stadium |
| Texas @ Oakland | 4:07 PM | RingCentral Coliseum |
| NY Mets @ Arizona | 4:10 PM | Chase Field |
| LA Dodgers @ San Diego | 4:10 PM | Petco Park |
| Kansas City @ Seattle | 4:10 PM | T-Mobile Park |
| Milwaukee @ Philadelphia | 7:08 PM | Citizens Bank Park |
| Mon Apr 25 | Time | Location |
| SF Giants @ Milwaukee | 6:10 PM | American Family Field |
| Colorado @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Boston @ Toronto | 7:07 PM | Rogers Centre |
| NY Mets @ St. Louis | 7:45 PM | Busch Stadium |
| Houston @ Texas | 8:05 PM | Globe Life Field |
| Cleveland @ LA Angels | 9:38 PM | Angel Stadium |
| LA Dodgers @ Arizona | 9:40 PM | Chase Field |
| Tue Apr 26 | Time | Location |
| Milwaukee @ Pittsburgh | 6:35 PM | PNC Park |
| San Diego @ Cincinnati | 6:40 PM | Great American Ball Park |
| Seattle @ Tampa Bay | 6:40 PM | Tropicana Field |
| Colorado @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Miami @ Washington | 7:05 PM | Nationals Park |
| Baltimore @ NY Yankees | 7:05 PM | Yankee Stadium |
| Boston @ Toronto | 7:07 PM | Rogers Centre |
| Kansas City @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| Chi Cubs @ Atlanta | 7:20 PM | Truist Park |
| Detroit @ Minnesota | 7:40 PM | Target Field |
| NY Mets @ St. Louis | 7:45 PM | Busch Stadium |
| Houston @ Texas | 8:05 PM | Globe Life Field |
| Cleveland @ LA Angels | 9:38 PM | Angel Stadium |
| LA Dodgers @ Arizona | 9:40 PM | Chase Field |
| Oakland @ SF Giants | 9:45 PM | Oracle Park |
| Wed Apr 27 | Time | Location |
| NY Mets @ St. Louis | 1:15 PM | Busch Stadium |
| Kansas City @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| LA Dodgers @ Arizona | 3:40 PM | Chase Field |
| Milwaukee @ Pittsburgh | 6:35 PM | PNC Park |
| San Diego @ Cincinnati | 6:40 PM | Great American Ball Park |
| Seattle @ Tampa Bay | 6:40 PM | Tropicana Field |
| Colorado @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Miami @ Washington | 7:05 PM | Nationals Park |
| Baltimore @ NY Yankees | 7:05 PM | Yankee Stadium |
| Boston @ Toronto | 7:07 PM | Rogers Centre |
| Chi Cubs @ Atlanta | 7:20 PM | Truist Park |
| Detroit @ Minnesota | 7:40 PM | Target Field |
| Houston @ Texas | 8:05 PM | Globe Life Field |
| Cleveland @ LA Angels | 9:38 PM | Angel Stadium |
| Oakland @ SF Giants | 9:45 PM | Oracle Park |
| Thu Apr 28 | Time | Location |
| San Diego @ Cincinnati | 12:35 PM | Great American Ball Park |
| Milwaukee @ Pittsburgh | 12:35 PM | PNC Park |
| Miami @ Washington | 1:05 PM | Nationals Park |
| Baltimore @ NY Yankees | 1:05 PM | Yankee Stadium |
| Colorado @ Philadelphia | 1:05 PM | Citizens Bank Park |
| Seattle @ Tampa Bay | 1:10 PM | Tropicana Field |
| Detroit @ Minnesota | 1:10 PM | Target Field |
| Houston @ Texas | 2:05 PM | Globe Life Field |
| Kansas City @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Boston @ Toronto | 3:07 PM | Rogers Centre |
| Cleveland @ LA Angels | 4:07 PM | Angel Stadium |
| Chi Cubs @ Atlanta | 7:20 PM | Truist Park |
| Arizona @ St. Louis | 7:45 PM | Busch Stadium |
| Fri Apr 29 | Time | Location |
| San Diego @ Pittsburgh | 6:35 PM | PNC Park |
| Seattle @ Miami | 6:40 PM | loanDepot Park |
| Boston @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Houston @ Toronto | 7:07 PM | Rogers Centre |
| Minnesota @ Tampa Bay | 7:10 PM | Tropicana Field |
| Philadelphia @ NY Mets | 7:10 PM | Citi Field |
| LA Angels @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| Atlanta @ Texas | 8:05 PM | Globe Life Field |
| Chi Cubs @ Milwaukee | 8:10 PM | American Family Field |
| NY Yankees @ Kansas City | 8:10 PM | Kauffman Stadium |
| Arizona @ St. Louis | 8:15 PM | Busch Stadium |
| Cincinnati @ Colorado | 8:40 PM | Coors Field |
| Cleveland @ Oakland | 9:40 PM | RingCentral Coliseum |
| Detroit @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Washington @ SF Giants | 10:15 PM | Oracle Park |
| Sat Apr 30 | Time | Location |
| Arizona @ St. Louis | 2:15 PM | Busch Stadium |
| Houston @ Toronto | 3:07 PM | Rogers Centre |
| Washington @ SF Giants | 4:05 PM | Oracle Park |
| LA Angels @ Chi Sox | 4:05 PM | Guaranteed Rate Field |
| Cleveland @ Oakland | 4:07 PM | RingCentral Coliseum |
| Minnesota @ Tampa Bay | 4:10 PM | Tropicana Field |
| Seattle @ Miami | 6:10 PM | loanDepot Park |
| San Diego @ Pittsburgh | 6:35 PM | PNC Park |
| Boston @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Atlanta @ Texas | 7:05 PM | Globe Life Field |
| NY Yankees @ Kansas City | 7:10 PM | Kauffman Stadium |
| Chi Cubs @ Milwaukee | 7:10 PM | American Family Field |
| Philadelphia @ NY Mets | 7:10 PM | Citi Field |
| Cincinnati @ Colorado | 8:10 PM | Coors Field |
| Detroit @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sun May 1 | Time | Location |
| Boston @ Baltimore | 1:05 PM | Oriole Park at Camden Yards |
| Minnesota @ Tampa Bay | 1:10 PM | Tropicana Field |
| San Diego @ Pittsburgh | 1:35 PM | PNC Park |
| Houston @ Toronto | 1:37 PM | Rogers Centre |
| Seattle @ Miami | 1:40 PM | loanDepot Park |
| Chi Cubs @ Milwaukee | 2:10 PM | American Family Field |
| LA Angels @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| NY Yankees @ Kansas City | 2:10 PM | Kauffman Stadium |
| Arizona @ St. Louis | 2:15 PM | Busch Stadium |
| Atlanta @ Texas | 2:35 PM | Globe Life Field |
| Cincinnati @ Colorado | 3:10 PM | Coors Field |
| Washington @ SF Giants | 4:05 PM | Oracle Park |
| Cleveland @ Oakland | 4:07 PM | RingCentral Coliseum |
| Detroit @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Philadelphia @ NY Mets | 7:08 PM | Citi Field |
| Mon May 2 | Time | Location |
| Kansas City @ St. Louis | 1:15 PM | Busch Stadium |
| LA Angels @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Arizona @ Miami | 6:40 PM | loanDepot Park |
| Minnesota @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| NY Yankees @ Toronto | 7:07 PM | Rogers Centre |
| Atlanta @ NY Mets | 7:10 PM | Citi Field |
| Seattle @ Houston | 8:10 PM | Minute Maid Park |
| Tampa Bay @ Oakland | 9:40 PM | RingCentral Coliseum |
| Tue May 3 | Time | Location |
| Atlanta @ NY Mets | 3:10 PM | Citi Field |
| Atlanta @ NY Mets | 6:10 PM | Citi Field |
| Arizona @ Miami | 6:40 PM | loanDepot Park |
| Texas @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Minnesota @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| NY Yankees @ Toronto | 7:07 PM | Rogers Centre |
| LA Angels @ Boston | 7:10 PM | Fenway Park |
| Chi Sox @ Chi Cubs | 7:40 PM | Wrigley Field |
| Cincinnati @ Milwaukee | 7:40 PM | American Family Field |
| Seattle @ Houston | 8:10 PM | Minute Maid Park |
| St. Louis @ Kansas City | 8:10 PM | Kauffman Stadium |
| Washington @ Colorado | 8:40 PM | Coors Field |
| Tampa Bay @ Oakland | 9:40 PM | RingCentral Coliseum |
| SF Giants @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed May 4 | Time | Location |
| Arizona @ Miami | 12:40 PM | loanDepot Park |
| Pittsburgh @ Detroit | 1:10 PM | Comerica Park |
| San Diego @ Cleveland | 1:10 PM | Progressive Field |
| Atlanta @ NY Mets | 1:10 PM | Citi Field |
| St. Louis @ Kansas City | 1:10 PM | Kauffman Stadium |
| Seattle @ Houston | 2:10 PM | Minute Maid Park |
| Tampa Bay @ Oakland | 3:37 PM | RingCentral Coliseum |
| Pittsburgh @ Detroit | 4:10 PM | Comerica Park |
| San Diego @ Cleveland | 4:10 PM | Progressive Field |
| Texas @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Minnesota @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| NY Yankees @ Toronto | 7:07 PM | Rogers Centre |
| LA Angels @ Boston | 7:10 PM | Fenway Park |
| Chi Sox @ Chi Cubs | 7:40 PM | Wrigley Field |
| Cincinnati @ Milwaukee | 7:40 PM | American Family Field |
| Washington @ Colorado | 8:40 PM | Coors Field |
| SF Giants @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Thu May 5 | Time | Location |
| LA Angels @ Boston | 1:35 PM | Fenway Park |
| Cincinnati @ Milwaukee | 1:40 PM | American Family Field |
| Washington @ Colorado | 3:10 PM | Coors Field |
| Toronto @ Cleveland | 6:10 PM | Progressive Field |
| NY Mets @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Minnesota @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Detroit @ Houston | 8:10 PM | Minute Maid Park |
| Miami @ San Diego | 9:40 PM | Petco Park |
| Tampa Bay @ Seattle | 9:40 PM | T-Mobile Park |
| St. Louis @ SF Giants | 9:45 PM | Oracle Park |
| Fri May 6 | Time | Location |
| Chi Sox @ Boston | 7:10 PM | Fenway Park |
| Milwaukee @ Atlanta | 7:20 PM | Truist Park |
| Detroit @ Houston | 8:10 PM | Minute Maid Park |
| Oakland @ Minnesota | 8:10 PM | Target Field |
| Washington @ LA Angels | 9:38 PM | Angel Stadium |
| Colorado @ Arizona | 9:40 PM | Chase Field |
| Tampa Bay @ Seattle | 9:40 PM | T-Mobile Park |
| Miami @ San Diego | 9:40 PM | Petco Park |
| St. Louis @ SF Giants | 10:15 PM | Oracle Park |
| Sat May 7 | Time | Location |
| Pittsburgh @ Cincinnati | 12:35 PM | Great American Ball Park |
| LA Dodgers @ Chi Cubs | 1:05 PM | Wrigley Field |
| Oakland @ Minnesota | 2:10 PM | Target Field |
| Toronto @ Cleveland | 2:10 PM | Progressive Field |
| Detroit @ Houston | 4:05 PM | Minute Maid Park |
| Chi Sox @ Boston | 4:10 PM | Fenway Park |
| Toronto @ Cleveland | 5:10 PM | Progressive Field |
| Pittsburgh @ Cincinnati | 6:40 PM | Great American Ball Park |
| St. Louis @ SF Giants | 7:15 PM | Oracle Park |
| Milwaukee @ Atlanta | 7:20 PM | Truist Park |
| LA Dodgers @ Chi Cubs | 7:40 PM | Wrigley Field |
| Colorado @ Arizona | 8:10 PM | Chase Field |
| Miami @ San Diego | 8:40 PM | Petco Park |
| Washington @ LA Angels | 9:07 PM | Angel Stadium |
| Tampa Bay @ Seattle | 9:10 PM | T-Mobile Park |
| Sun May 8 | Time | Location |
| Chi Sox @ Boston | 11:35 AM | Fenway Park |
| NY Mets @ Philadelphia | 12:35 PM | Citizens Bank Park |
| Texas @ NY Yankees | 1:35 PM | Yankee Stadium |
| Milwaukee @ Atlanta | 1:35 PM | Truist Park |
| Kansas City @ Baltimore | 1:35 PM | Oriole Park at Camden Yards |
| Pittsburgh @ Cincinnati | 1:40 PM | Great American Ball Park |
| Toronto @ Cleveland | 1:40 PM | Progressive Field |
| Detroit @ Houston | 2:10 PM | Minute Maid Park |
| Oakland @ Minnesota | 2:10 PM | Target Field |
| NY Mets @ Philadelphia | 3:35 PM | Citizens Bank Park |
| St. Louis @ SF Giants | 4:05 PM | Oracle Park |
| Washington @ LA Angels | 4:07 PM | Angel Stadium |
| Colorado @ Arizona | 4:10 PM | Chase Field |
| Tampa Bay @ Seattle | 4:10 PM | T-Mobile Park |
| Miami @ San Diego | 4:10 PM | Petco Park |
| Texas @ NY Yankees | 4:35 PM | Yankee Stadium |
| Kansas City @ Baltimore | 4:35 PM | Oriole Park at Camden Yards |
| LA Dodgers @ Chi Cubs | 7:08 PM | Wrigley Field |
| Mon May 9 | Time | Location |
| Kansas City @ Baltimore | 12:05 PM | Oriole Park at Camden Yards |
| Texas @ NY Yankees | 1:05 PM | Yankee Stadium |
| LA Dodgers @ Pittsburgh | 6:35 PM | PNC Park |
| Milwaukee @ Cincinnati | 6:40 PM | Great American Ball Park |
| Oakland @ Detroit | 7:10 PM | Comerica Park |
| Cleveland @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Tampa Bay @ LA Angels | 9:38 PM | Angel Stadium |
| Philadelphia @ Seattle | 9:40 PM | T-Mobile Park |
| Chi Cubs @ San Diego | 9:40 PM | Petco Park |
| Miami @ Arizona | 9:40 PM | Chase Field |
| Colorado @ SF Giants | 9:45 PM | Oracle Park |
| Tue May 10 | Time | Location |
| Detroit vs. Oakland | 1:10 PM | Comerica Park |
| Oakland @ Detroit | 4:10 PM | Comerica Park |
| LA Dodgers @ Pittsburgh | 6:35 PM | PNC Park |
| Milwaukee @ Cincinnati | 6:40 PM | Great American Ball Park |
| NY Mets @ Washington | 7:05 PM | Nationals Park |
| Toronto @ NY Yankees | 7:05 PM | Yankee Stadium |
| Boston @ Atlanta | 7:20 PM | Truist Park |
| Houston @ Minnesota | 7:40 PM | Target Field |
| Baltimore @ St. Louis | 7:45 PM | Busch Stadium |
| Kansas City @ Texas | 8:05 PM | Globe Life Field |
| Cleveland @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Tampa Bay @ LA Angels | 9:38 PM | Angel Stadium |
| Chi Cubs @ San Diego | 9:40 PM | Petco Park |
| Miami @ Arizona | 9:40 PM | Chase Field |
| Philadelphia @ Seattle | 9:40 PM | T-Mobile Park |
| Colorado @ SF Giants | 9:45 PM | Oracle Park |
| Wed May 11 | Time | Location |
| LA Dodgers @ Pittsburgh | 12:35 PM | PNC Park |
| Toronto @ NY Yankees | 12:35 PM | Yankee Stadium |
| Milwaukee @ Cincinnati | 12:35 PM | Great American Ball Park |
| Miami @ Arizona | 3:40 PM | Chase Field |
| Philadelphia @ Seattle | 3:40 PM | T-Mobile Park |
| Colorado @ SF Giants | 3:45 PM | Oracle Park |
| Chi Cubs @ San Diego | 4:10 PM | Petco Park |
| NY Mets @ Washington | 7:05 PM | Nationals Park |
| Tampa Bay @ LA Angels | 7:07 PM | Angel Stadium |
| Oakland @ Detroit | 7:10 PM | Comerica Park |
| Boston @ Atlanta | 7:20 PM | Truist Park |
| Houston @ Minnesota | 7:40 PM | Target Field |
| Baltimore @ St. Louis | 7:45 PM | Busch Stadium |
| Kansas City @ Texas | 8:05 PM | Globe Life Field |
| Thu May 12 | Time | Location |
| NY Mets @ Washington | 1:05 PM | Nationals Park |
| Oakland @ Detroit | 1:10 PM | Comerica Park |
| Baltimore @ St. Louis | 1:15 PM | Busch Stadium |
| Houston @ Minnesota | 3:10 PM | Target Field |
| Cincinnati @ Pittsburgh | 6:35 PM | PNC Park |
| Kansas City @ Texas | 8:05 PM | Globe Life Field |
| NY Yankees @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Philadelphia @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Fri May 13 | Time | Location |
| Cincinnati @ Pittsburgh | 6:35 PM | PNC Park |
| Milwaukee @ Miami | 6:40 PM | loanDepot Park |
| Houston @ Washington | 7:05 PM | Nationals Park |
| Baltimore @ Detroit | 7:10 PM | Comerica Park |
| Seattle @ NY Mets | 7:10 PM | Citi Field |
| Toronto @ Tampa Bay | 7:10 PM | Tropicana Field |
| San Diego @ Atlanta | 7:20 PM | Truist Park |
| Boston @ Texas | 8:05 PM | Globe Life Field |
| NY Yankees @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Cleveland @ Minnesota | 8:10 PM | Target Field |
| SF Giants @ St. Louis | 8:15 PM | Busch Stadium |
| Kansas City @ Colorado | 8:40 PM | Coors Field |
| LA Angels @ Oakland | 9:40 PM | RingCentral Coliseum |
| Chi Cubs @ Arizona | 9:40 PM | Chase Field |
| Philadelphia @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sat May 14 | Time | Location |
| SF Giants @ St. Louis | 2:15 PM | Busch Stadium |
| San Diego @ Atlanta | 4:05 PM | Truist Park |
| LA Angels @ Oakland | 4:07 PM | RingCentral Coliseum |
| Baltimore @ Detroit | 4:10 PM | Comerica Park |
| Milwaukee @ Miami | 6:10 PM | loanDepot Park |
| Toronto @ Tampa Bay | 6:10 PM | Tropicana Field |
| Cincinnati @ Pittsburgh | 6:35 PM | PNC Park |
| Boston @ Texas | 7:05 PM | Globe Life Field |
| Houston @ Washington | 7:05 PM | Nationals Park |
| NY Yankees @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| Seattle @ NY Mets | 7:10 PM | Citi Field |
| Cleveland @ Minnesota | 7:10 PM | Target Field |
| Chi Cubs @ Arizona | 8:10 PM | Chase Field |
| Kansas City @ Colorado | 8:10 PM | Coors Field |
| LA Angels @ Oakland | 9:40 PM | RingCentral Coliseum |
| Philadelphia @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sun May 15 | Time | Location |
| San Diego @ Atlanta | 11:35 AM | Truist Park |
| Houston @ Washington | 1:35 PM | Nationals Park |
| Cincinnati @ Pittsburgh | 1:35 PM | PNC Park |
| Seattle @ NY Mets | 1:40 PM | Citi Field |
| Toronto @ Tampa Bay | 1:40 PM | Tropicana Field |
| Baltimore @ Detroit | 1:40 PM | Comerica Park |
| Milwaukee @ Miami | 1:40 PM | loanDepot Park |
| Cleveland @ Minnesota | 2:10 PM | Target Field |
| NY Yankees @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Boston @ Texas | 2:35 PM | Globe Life Field |
| Kansas City @ Colorado | 3:10 PM | Coors Field |
| LA Angels @ Oakland | 4:07 PM | RingCentral Coliseum |
| Philadelphia @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Chi Cubs @ Arizona | 4:10 PM | Chase Field |
| SF Giants @ St. Louis | 7:08 PM | Busch Stadium |
| Mon May 16 | Time | Location |
| Washington @ Miami | 6:40 PM | loanDepot Park |
| Detroit @ Tampa Bay | 6:40 PM | Tropicana Field |
| NY Yankees @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Seattle @ Toronto | 7:07 PM | Rogers Centre |
| Houston @ Boston | 7:10 PM | Fenway Park |
| Pittsburgh @ Chi Cubs | 7:40 PM | Wrigley Field |
| Atlanta @ Milwaukee | 7:40 PM | American Family Field |
| LA Angels @ Texas | 8:05 PM | Globe Life Field |
| Chi Sox @ Kansas City | 8:10 PM | Kauffman Stadium |
| SF Giants @ Colorado | 8:40 PM | Coors Field |
| Minnesota @ Oakland | 9:40 PM | RingCentral Coliseum |
| Arizona @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Tue May 17 | Time | Location |
| Chi Sox @ Kansas City | 2:10 PM | Kauffman Stadium |
| Arizona @ LA Dodgers | 3:10 PM | Dodger Stadium |
| St. Louis @ NY Mets | 3:10 PM | Citi Field |
| Cincinnati @ Cleveland | 6:10 PM | Progressive Field |
| St. Louis @ NY Mets | 6:10 PM | Citi Field |
| Detroit @ Tampa Bay | 6:40 PM | Tropicana Field |
| Washington @ Miami | 6:40 PM | loanDepot Park |
| San Diego @ Philadelphia | 6:45 PM | Citizens Bank Park |
| NY Yankees @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Seattle @ Toronto | 7:07 PM | Rogers Centre |
| Houston @ Boston | 7:10 PM | Fenway Park |
| Chi Sox @ Kansas City | 7:10 PM | Kauffman Stadium |
| Pittsburgh @ Chi Cubs | 7:40 PM | Wrigley Field |
| Atlanta @ Milwaukee | 7:40 PM | American Family Field |
| LA Angels @ Texas | 8:05 PM | Globe Life Field |
| SF Giants @ Colorado | 8:40 PM | Coors Field |
| Minnesota @ Oakland | 9:40 PM | RingCentral Coliseum |
| Arizona @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed May 18 | Time | Location |
| Atlanta @ Milwaukee | 1:10 PM | American Family Field |
| Detroit @ Tampa Bay | 1:10 PM | Tropicana Field |
| SF Giants @ Colorado | 3:10 PM | Coors Field |
| Minnesota @ Oakland | 3:37 PM | RingCentral Coliseum |
| Arizona @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Houston @ Boston | 6:10 PM | Fenway Park |
| Washington @ Miami | 6:40 PM | loanDepot Park |
| San Diego @ Philadelphia | 6:45 PM | Citizens Bank Park |
| NY Yankees @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Seattle @ Toronto | 7:07 PM | Rogers Centre |
| St. Louis @ NY Mets | 7:10 PM | Citi Field |
| Pittsburgh @ Chi Cubs | 7:40 PM | Wrigley Field |
| LA Angels @ Texas | 8:05 PM | Globe Life Field |
| Chi Sox @ Kansas City | 8:10 PM | Kauffman Stadium |
| Thu May 19 | Time | Location |
| NY Yankees @ Baltimore | 12:35 PM | Oriole Park at Camden Yards |
| San Diego @ Philadelphia | 1:05 PM | Citizens Bank Park |
| St. Louis @ NY Mets | 1:10 PM | Citi Field |
| Cincinnati @ Cleveland | 1:10 PM | Progressive Field |
| Chi Sox @ Kansas City | 2:10 PM | Kauffman Stadium |
| Seattle @ Boston | 7:10 PM | Fenway Park |
| Arizona @ Chi Cubs | 7:40 PM | Wrigley Field |
| Texas @ Houston | 8:10 PM | Minute Maid Park |
| Fri May 20 | Time | Location |
| Arizona @ Chi Cubs | 2:20 PM | Wrigley Field |
| St. Louis @ Pittsburgh | 6:35 PM | PNC Park |
| Atlanta @ Miami | 6:40 PM | loanDepot Park |
| Tampa Bay @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| LA Dodgers @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Cincinnati @ Toronto | 7:07 PM | Rogers Centre |
| Seattle @ Boston | 7:10 PM | Fenway Park |
| Detroit @ Cleveland | 7:10 PM | Progressive Field |
| Texas @ Houston | 8:10 PM | Minute Maid Park |
| Minnesota @ Kansas City | 8:10 PM | Kauffman Stadium |
| Washington @ Milwaukee | 8:10 PM | American Family Field |
| Oakland @ LA Angels | 9:38 PM | Angel Stadium |
| San Diego @ SF Giants | 10:15 PM | Oracle Park |
| Sat May 21 | Time | Location |
| Chi Sox @ NY Yankees | 1:05 PM | Yankee Stadium |
| Arizona @ Chi Cubs | 2:20 PM | Wrigley Field |
| Cincinnati @ Toronto | 3:07 PM | Rogers Centre |
| NY Mets @ Colorado | 3:10 PM | Coors Field |
| San Diego @ SF Giants | 4:05 PM | Oracle Park |
| Seattle @ Boston | 4:10 PM | Fenway Park |
| LA Dodgers @ Philadelphia | 6:05 PM | Citizens Bank Park |
| Atlanta @ Miami | 6:10 PM | loanDepot Park |
| St. Louis @ Pittsburgh | 6:35 PM | PNC Park |
| Tampa Bay @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Texas @ Houston | 7:10 PM | Minute Maid Park |
| Minnesota @ Kansas City | 7:10 PM | Kauffman Stadium |
| Washington @ Milwaukee | 7:10 PM | American Family Field |
| NY Mets @ Colorado | 8:40 PM | Coors Field |
| Oakland @ LA Angels | 9:07 PM | Angel Stadium |
| Sun May 22 | Time | Location |
| St. Louis @ Pittsburgh | 11:35 AM | PNC Park |
| Seattle @ Boston | 1:35 PM | Fenway Park |
| Tampa Bay @ Baltimore | 1:35 PM | Oriole Park at Camden Yards |
| LA Dodgers @ Philadelphia | 1:35 PM | Citizens Bank Park |
| Cincinnati @ Toronto | 1:37 PM | Rogers Centre |
| Detroit @ Cleveland | 1:40 PM | Progressive Field |
| Atlanta @ Miami | 1:40 PM | loanDepot Park |
| Washington @ Milwaukee | 2:10 PM | American Family Field |
| Minnesota @ Kansas City | 2:10 PM | Kauffman Stadium |
| Texas @ Houston | 2:10 PM | Minute Maid Park |
| Arizona @ Chi Cubs | 2:20 PM | Wrigley Field |
| Chi Sox @ NY Yankees | 3:05 PM | Yankee Stadium |
| NY Mets @ Colorado | 3:10 PM | Coors Field |
| San Diego @ SF Giants | 4:05 PM | Oracle Park |
| Oakland @ LA Angels | 4:07 PM | Angel Stadium |
| Chi Sox @ NY Yankees | 7:08 PM | Yankee Stadium |
| Mon May 23 | Time | Location |
| Colorado @ Pittsburgh | 6:35 PM | PNC Park |
| Chi Cubs @ Cincinnati | 6:40 PM | Great American Ball Park |
| LA Dodgers @ Washington | 7:05 PM | Nationals Park |
| Baltimore @ NY Yankees | 7:05 PM | Yankee Stadium |
| Philadelphia @ Atlanta | 7:20 PM | Truist Park |
| Detroit @ Minnesota | 7:40 PM | Target Field |
| Toronto @ St. Louis | 7:45 PM | Busch Stadium |
| Cleveland @ Houston | 8:10 PM | Minute Maid Park |
| Kansas City @ Arizona | 9:40 PM | Chase Field |
| Milwaukee @ San Diego | 9:40 PM | Petco Park |
| Oakland @ Seattle | 9:40 PM | T-Mobile Park |
| NY Mets @ SF Giants | 9:45 PM | Oracle Park |
| Tue May 24 | Time | Location |
| Colorado @ Pittsburgh | 6:35 PM | PNC Park |
| Chi Cubs @ Cincinnati | 6:40 PM | Great American Ball Park |
| Miami @ Tampa Bay | 6:40 PM | Tropicana Field |
| Baltimore @ NY Yankees | 7:05 PM | Yankee Stadium |
| LA Dodgers @ Washington | 7:05 PM | Nationals Park |
| Philadelphia @ Atlanta | 7:20 PM | Truist Park |
| Detroit @ Minnesota | 7:40 PM | Target Field |
| Toronto @ St. Louis | 7:45 PM | Busch Stadium |
| Boston @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Cleveland @ Houston | 8:10 PM | Minute Maid Park |
| Texas @ LA Angels | 9:38 PM | Angel Stadium |
| Kansas City @ Arizona | 9:40 PM | Chase Field |
| Oakland @ Seattle | 9:40 PM | T-Mobile Park |
| Milwaukee @ San Diego | 9:40 PM | Petco Park |
| NY Mets @ SF Giants | 9:45 PM | Oracle Park |
| Wed May 25 | Time | Location |
| Colorado @ Pittsburgh | 12:35 PM | PNC Park |
| Detroit @ Minnesota | 1:10 PM | Target Field |
| NY Mets @ SF Giants | 3:45 PM | Oracle Park |
| LA Dodgers @ Washington | 4:05 PM | Nationals Park |
| Milwaukee @ San Diego | 4:10 PM | Petco Park |
| Oakland @ Seattle | 4:10 PM | T-Mobile Park |
| Chi Cubs @ Cincinnati | 6:40 PM | Great American Ball Park |
| Miami @ Tampa Bay | 6:40 PM | Tropicana Field |
| Baltimore @ NY Yankees | 7:05 PM | Yankee Stadium |
| Philadelphia @ Atlanta | 7:20 PM | Truist Park |
| Boston @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Cleveland @ Houston | 8:10 PM | Minute Maid Park |
| Texas @ LA Angels | 9:38 PM | Angel Stadium |
| Thu May 26 | Time | Location |
| Chi Cubs @ Cincinnati | 12:35 PM | Great American Ball Park |
| NY Yankees @ Tampa Bay | 6:40 PM | Tropicana Field |
| Colorado @ Washington | 7:05 PM | Nationals Park |
| Cleveland @ Detroit | 7:10 PM | Comerica Park |
| Philadelphia @ Atlanta | 7:20 PM | Truist Park |
| Kansas City @ Minnesota | 7:40 PM | Target Field |
| Milwaukee @ St. Louis | 7:45 PM | Busch Stadium |
| Boston @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Toronto @ LA Angels | 9:38 PM | Angel Stadium |
| Texas @ Oakland | 9:40 PM | RingCentral Coliseum |
| LA Dodgers @ Arizona | 9:40 PM | Chase Field |
| Fri May 27 | Time | Location |
| SF Giants @ Cincinnati | 6:40 PM | Great American Ball Park |
| Baltimore @ Boston | 7:10 PM | Fenway Park |
| Philadelphia @ NY Mets | 7:10 PM | Citi Field |
| NY Yankees @ Tampa Bay | 7:10 PM | Tropicana Field |
| Miami @ Atlanta | 7:20 PM | Truist Park |
| Kansas City @ Minnesota | 8:10 PM | Target Field |
| Milwaukee @ St. Louis | 8:15 PM | Busch Stadium |
| Toronto @ LA Angels | 9:38 PM | Angel Stadium |
| Texas @ Oakland | 9:40 PM | RingCentral Coliseum |
| LA Dodgers @ Arizona | 9:40 PM | Chase Field |
| Pittsburgh @ San Diego | 9:40 PM | Petco Park |
| Houston @ Seattle | 9:40 PM | T-Mobile Park |
| Sat May 28 | Time | Location |
| Colorado @ Washington | 12:05 PM | Nationals Park |
| Baltimore @ Boston | 12:10 PM | Fenway Park |
| Kansas City @ Minnesota | 2:10 PM | Target Field |
| Milwaukee @ St. Louis | 2:15 PM | Busch Stadium |
| Texas @ Oakland | 4:07 PM | RingCentral Coliseum |
| Miami @ Atlanta | 4:10 PM | Truist Park |
| NY Yankees @ Tampa Bay | 4:10 PM | Tropicana Field |
| SF Giants @ Cincinnati | 4:10 PM | Great American Ball Park |
| Cleveland @ Detroit | 4:10 PM | Comerica Park |
| Colorado @ Washington | 6:05 PM | Nationals Park |
| Baltimore @ Boston | 6:10 PM | Fenway Park |
| LA Dodgers @ Arizona | 7:15 PM | Chase Field |
| Philadelphia @ NY Mets | 7:15 PM | Citi Field |
| Chi Cubs @ Chi Sox | 7:15 PM | Guaranteed Rate Field |
| Toronto @ LA Angels | 10:07 PM | Angel Stadium |
| Pittsburgh @ San Diego | 10:10 PM | Petco Park |
| Houston @ Seattle | 10:10 PM | T-Mobile Park |
| Sun May 29 | Time | Location |
| SF Giants @ Cincinnati | 11:35 AM | Great American Ball Park |
| Baltimore @ Boston | 1:35 PM | Fenway Park |
| Colorado @ Washington | 1:35 PM | Nationals Park |
| Miami @ Atlanta | 1:35 PM | Truist Park |
| NY Yankees @ Tampa Bay | 1:40 PM | Tropicana Field |
| Cleveland @ Detroit | 1:40 PM | Comerica Park |
| Kansas City @ Minnesota | 2:10 PM | Target Field |
| Chi Cubs @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Milwaukee @ St. Louis | 2:15 PM | Busch Stadium |
| Texas @ Oakland | 4:07 PM | RingCentral Coliseum |
| Toronto @ LA Angels | 4:07 PM | Angel Stadium |
| LA Dodgers @ Arizona | 4:10 PM | Chase Field |
| Pittsburgh @ San Diego | 4:10 PM | Petco Park |
| Houston @ Seattle | 4:10 PM | T-Mobile Park |
| Philadelphia @ NY Mets | 7:08 PM | Citi Field |
| Mon May 30 | Time | Location |
| Milwaukee @ Chi Cubs | 1:05 PM | Wrigley Field |
| Minnesota @ Detroit | 1:10 PM | Comerica Park |
| San Diego @ St. Louis | 2:15 PM | Busch Stadium |
| SF Giants @ Philadelphia | 4:05 PM | Citizens Bank Park |
| Houston @ Oakland | 4:07 PM | RingCentral Coliseum |
| Miami @ Colorado | 4:10 PM | Coors Field |
| Kansas City @ Cleveland | 6:10 PM | Progressive Field |
| Washington @ NY Mets | 7:10 PM | Citi Field |
| Baltimore @ Boston | 7:10 PM | Fenway Park |
| Milwaukee @ Chi Cubs | 7:40 PM | Wrigley Field |
| Tampa Bay @ Texas | 8:05 PM | Globe Life Field |
| Atlanta @ Arizona | 8:10 PM | Chase Field |
| Pittsburgh @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Tue May 31 | Time | Location |
| Minnesota @ Detroit | 1:10 PM | Comerica Park |
| Kansas City @ Cleveland | 6:10 PM | Progressive Field |
| SF Giants @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Seattle @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| LA Angels @ NY Yankees | 7:05 PM | Yankee Stadium |
| Chi Sox @ Toronto | 7:07 PM | Rogers Centre |
| Washington @ NY Mets | 7:10 PM | Citi Field |
| Minnesota @ Detroit | 7:10 PM | Comerica Park |
| Cincinnati @ Boston | 7:10 PM | Fenway Park |
| San Diego @ St. Louis | 7:45 PM | Busch Stadium |
| Tampa Bay @ Texas | 8:05 PM | Globe Life Field |
| Milwaukee @ Chi Cubs | 8:05 PM | Wrigley Field |
| Atlanta @ Arizona | 9:40 PM | Chase Field |
| Houston @ Oakland | 9:40 PM | RingCentral Coliseum |
| Pittsburgh @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed Jun 1 | Time | Location |
| Kansas City @ Cleveland | 1:10 PM | Progressive Field |
| Washington @ NY Mets | 1:10 PM | Citi Field |
| San Diego @ St. Louis | 1:15 PM | Busch Stadium |
| Miami @ Colorado | 3:10 PM | Coors Field |
| Houston @ Oakland | 3:37 PM | RingCentral Coliseum |
| Atlanta @ Arizona | 3:40 PM | Chase Field |
| SF Giants @ Philadelphia | 6:05 PM | Citizens Bank Park |
| Miami @ Colorado | 6:10 PM | Coors Field |
| Seattle @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Chi Sox @ Toronto | 7:07 PM | Rogers Centre |
| Minnesota @ Detroit | 7:10 PM | Comerica Park |
| Cincinnati @ Boston | 7:10 PM | Fenway Park |
| Tampa Bay @ Texas | 8:05 PM | Globe Life Field |
| Milwaukee @ Chi Cubs | 8:05 PM | Wrigley Field |
| Pittsburgh @ LA Dodgers | 8:10 PM | Dodger Stadium |
| Thu Jun 2 | Time | Location |
| LA Angels @ NY Yankees | 1:05 PM | Yankee Stadium |
| Minnesota @ Detroit | 1:10 PM | Comerica Park |
| Tampa Bay @ Texas | 2:05 PM | Globe Life Field |
| Chi Sox @ Toronto | 3:07 PM | Rogers Centre |
| SF Giants @ Miami | 6:40 PM | loanDepot Park |
| Washington @ Cincinnati | 6:40 PM | Great American Ball Park |
| Seattle @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| LA Angels @ NY Yankees | 7:05 PM | Yankee Stadium |
| San Diego @ Milwaukee | 7:40 PM | American Family Field |
| St. Louis @ Chi Cubs | 8:05 PM | Wrigley Field |
| Atlanta @ Colorado | 8:40 PM | Coors Field |
| NY Mets @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Fri Jun 3 | Time | Location |
| St. Louis @ Chi Cubs | 2:20 PM | Wrigley Field |
| SF Giants @ Miami | 6:40 PM | loanDepot Park |
| Washington @ Cincinnati | 6:40 PM | Great American Ball Park |
| Arizona @ Pittsburgh | 7:05 PM | PNC Park |
| LA Angels @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Cleveland @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Detroit @ NY Yankees | 7:05 PM | Yankee Stadium |
| Minnesota @ Toronto | 7:07 PM | Rogers Centre |
| Chi Sox @ Tampa Bay | 7:10 PM | Tropicana Field |
| Seattle @ Texas | 8:05 PM | Globe Life Field |
| Houston @ Kansas City | 8:10 PM | Kauffman Stadium |
| San Diego @ Milwaukee | 8:10 PM | American Family Field |
| Atlanta @ Colorado | 8:40 PM | Coors Field |
| Boston @ Oakland | 9:40 PM | RingCentral Coliseum |
| NY Mets @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sat Jun 4 | Time | Location |
| Detroit @ NY Yankees | 1:05 PM | Yankee Stadium |
| St. Louis @ Chi Cubs | 1:20 PM | Wrigley Field |
| Minnesota @ Toronto | 3:07 PM | Rogers Centre |
| Arizona @ Pittsburgh | 4:05 PM | PNC Park |
| Seattle @ Texas | 4:05 PM | Globe Life Field |
| Cleveland @ Baltimore | 4:05 PM | Oriole Park at Camden Yards |
| Boston @ Oakland | 4:07 PM | RingCentral Coliseum |
| Chi Sox @ Tampa Bay | 4:10 PM | Tropicana Field |
| SF Giants @ Miami | 4:10 PM | loanDepot Park |
| San Diego @ Milwaukee | 4:10 PM | American Family Field |
| Houston @ Kansas City | 4:10 PM | Kauffman Stadium |
| Washington @ Cincinnati | 4:10 PM | Great American Ball Park |
| St. Louis @ Chi Cubs | 7:15 PM | Wrigley Field |
| LA Angels @ Philadelphia | 7:15 PM | Citizens Bank Park |
| Atlanta @ Colorado | 9:10 PM | Coors Field |
| NY Mets @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sun Jun 5 | Time | Location |
| Detroit @ NY Yankees | 11:35 AM | Yankee Stadium |
| Cleveland @ Baltimore | 1:35 PM | Oriole Park at Camden Yards |
| Arizona @ Pittsburgh | 1:35 PM | PNC Park |
| LA Angels @ Philadelphia | 1:35 PM | Citizens Bank Park |
| Minnesota @ Toronto | 1:37 PM | Rogers Centre |
| Washington @ Cincinnati | 1:40 PM | Great American Ball Park |
| SF Giants @ Miami | 1:40 PM | loanDepot Park |
| Chi Sox @ Tampa Bay | 1:40 PM | Tropicana Field |
| San Diego @ Milwaukee | 2:10 PM | American Family Field |
| Houston @ Kansas City | 2:10 PM | Kauffman Stadium |
| Seattle @ Texas | 2:35 PM | Globe Life Field |
| Atlanta @ Colorado | 3:10 PM | Coors Field |
| Boston @ Oakland | 4:07 PM | RingCentral Coliseum |
| NY Mets @ LA Dodgers | 4:10 PM | Dodger Stadium |
| St. Louis @ Chi Cubs | 7:08 PM | Wrigley Field |
| Mon Jun 6 | Time | Location |
| Arizona @ Cincinnati | 6:40 PM | Great American Ball Park |
| Toronto @ Kansas City | 8:10 PM | Kauffman Stadium |
| Seattle @ Houston | 8:10 PM | Minute Maid Park |
| Boston @ LA Angels | 9:38 PM | Angel Stadium |
| NY Mets @ San Diego | 9:40 PM | Petco Park |
| Tue Jun 7 | Time | Location |
| Texas @ Cleveland | 3:10 PM | Progressive Field |
| Texas @ Cleveland | 6:10 PM | Progressive Field |
| Washington @ Miami | 6:40 PM | loanDepot Park |
| Arizona @ Cincinnati | 6:40 PM | Great American Ball Park |
| Detroit @ Pittsburgh | 7:05 PM | PNC Park |
| Chi Cubs @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| St. Louis @ Tampa Bay | 7:10 PM | Tropicana Field |
| Oakland @ Atlanta | 7:20 PM | Truist Park |
| NY Yankees @ Minnesota | 7:40 PM | Target Field |
| Philadelphia @ Milwaukee | 8:10 PM | American Family Field |
| LA Dodgers @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Seattle @ Houston | 8:10 PM | Minute Maid Park |
| Toronto @ Kansas City | 8:10 PM | Kauffman Stadium |
| Boston @ LA Angels | 9:38 PM | Angel Stadium |
| NY Mets @ San Diego | 9:40 PM | Petco Park |
| Colorado @ SF Giants | 9:45 PM | Oracle Park |
| Wed Jun 8 | Time | Location |
| Detroit @ Pittsburgh | 12:35 PM | PNC Park |
| Toronto @ Kansas City | 2:10 PM | Kauffman Stadium |
| Seattle @ Houston | 6:40 PM | Minute Maid Park |
| Arizona @ Cincinnati | 6:40 PM | Great American Ball Park |
| Washington @ Miami | 6:40 PM | loanDepot Park |
| St. Louis @ Tampa Bay | 7:10 PM | Tropicana Field |
| Texas @ Cleveland | 7:10 PM | Progressive Field |
| Oakland @ Atlanta | 7:20 PM | Truist Park |
| NY Yankees @ Minnesota | 7:40 PM | Target Field |
| Philadelphia @ Milwaukee | 8:10 PM | American Family Field |
| LA Dodgers @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Boston @ LA Angels | 9:38 PM | Angel Stadium |
| NY Mets @ San Diego | 9:40 PM | Petco Park |
| Colorado @ SF Giants | 9:45 PM | Oracle Park |
| Thu Jun 9 | Time | Location |
| Arizona @ Cincinnati | 12:35 PM | Great American Ball Park |
| St. Louis @ Tampa Bay | 1:10 PM | Tropicana Field |
| LA Dodgers @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Philadelphia @ Milwaukee | 2:10 PM | American Family Field |
| Colorado @ SF Giants | 3:45 PM | Oracle Park |
| Washington @ Miami | 6:40 PM | loanDepot Park |
| Oakland @ Cleveland | 7:10 PM | Progressive Field |
| Pittsburgh @ Atlanta | 7:20 PM | Truist Park |
| NY Yankees @ Minnesota | 7:40 PM | Target Field |
| Baltimore @ Kansas City | 8:10 PM | Kauffman Stadium |
| Boston @ LA Angels | 9:38 PM | Angel Stadium |
| Fri Jun 10 | Time | Location |
| Arizona @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Chi Cubs @ NY Yankees | 7:05 PM | Yankee Stadium |
| Milwaukee @ Washington | 7:05 PM | Nationals Park |
| Toronto @ Detroit | 7:10 PM | Comerica Park |
| Oakland @ Cleveland | 7:10 PM | Progressive Field |
| Pittsburgh @ Atlanta | 7:20 PM | Truist Park |
| Texas @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Miami @ Houston | 8:10 PM | Minute Maid Park |
| Tampa Bay @ Minnesota | 8:10 PM | Target Field |
| Baltimore @ Kansas City | 8:10 PM | Kauffman Stadium |
| Cincinnati @ St. Louis | 8:15 PM | Busch Stadium |
| NY Mets @ LA Angels | 9:38 PM | Angel Stadium |
| Colorado @ San Diego | 9:40 PM | Petco Park |
| Boston @ Seattle | 10:10 PM | T-Mobile Park |
| LA Dodgers @ SF Giants | 10:15 PM | Oracle Park |
| Sat Jun 11 | Time | Location |
| Tampa Bay @ Minnesota | 2:10 PM | Target Field |
| Texas @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Cincinnati @ St. Louis | 2:15 PM | Busch Stadium |
| Arizona @ Philadelphia | 4:05 PM | Citizens Bank Park |
| Milwaukee @ Washington | 4:05 PM | Nationals Park |
| Pittsburgh @ Atlanta | 4:10 PM | Truist Park |
| Miami @ Houston | 4:10 PM | Minute Maid Park |
| Toronto @ Detroit | 4:10 PM | Comerica Park |
| Oakland @ Cleveland | 4:10 PM | Progressive Field |
| Baltimore @ Kansas City | 4:10 PM | Kauffman Stadium |
| Colorado @ San Diego | 4:10 PM | Petco Park |
| LA Dodgers @ SF Giants | 7:15 PM | Oracle Park |
| Chi Cubs @ NY Yankees | 7:15 PM | Yankee Stadium |
| NY Mets @ LA Angels | 10:07 PM | Angel Stadium |
| Colorado @ San Diego | 10:10 PM | Petco Park |
| Boston @ Seattle | 10:10 PM | T-Mobile Park |
| Sun Jun 12 | Time | Location |
| Oakland @ Cleveland | 11:35 AM | Progressive Field |
| Arizona @ Philadelphia | 1:35 PM | Citizens Bank Park |
| Pittsburgh @ Atlanta | 1:35 PM | Truist Park |
| Chi Cubs @ NY Yankees | 1:35 PM | Yankee Stadium |
| Milwaukee @ Washington | 1:35 PM | Nationals Park |
| Toronto @ Detroit | 1:40 PM | Comerica Park |
| Tampa Bay @ Minnesota | 2:10 PM | Target Field |
| Baltimore @ Kansas City | 2:10 PM | Kauffman Stadium |
| Texas @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Miami @ Houston | 2:10 PM | Minute Maid Park |
| Cincinnati @ St. Louis | 2:15 PM | Busch Stadium |
| LA Dodgers @ SF Giants | 4:05 PM | Oracle Park |
| Colorado @ San Diego | 4:10 PM | Petco Park |
| Boston @ Seattle | 4:10 PM | T-Mobile Park |
| NY Mets @ LA Angels | 7:08 PM | Angel Stadium |
| Mon Jun 13 | Time | Location |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| Miami @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Baltimore @ Toronto | 7:07 PM | Rogers Centre |
| Chi Sox @ Detroit | 7:10 PM | Comerica Park |
| Pittsburgh @ St. Louis | 7:45 PM | Busch Stadium |
| Houston @ Texas | 8:05 PM | Globe Life Field |
| San Diego @ Chi Cubs | 8:05 PM | Wrigley Field |
| Cincinnati @ Arizona | 9:40 PM | Chase Field |
| Kansas City @ SF Giants | 9:45 PM | Oracle Park |
| Minnesota @ Seattle | 10:10 PM | T-Mobile Park |
| Tue Jun 14 | Time | Location |
| Pittsburgh @ St. Louis | 1:15 PM | Busch Stadium |
| Miami @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Tampa Bay @ NY Yankees | 7:05 PM | Yankee Stadium |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| Baltimore @ Toronto | 7:07 PM | Rogers Centre |
| Oakland @ Boston | 7:10 PM | Fenway Park |
| Chi Sox @ Detroit | 7:10 PM | Comerica Park |
| Milwaukee @ NY Mets | 7:10 PM | Citi Field |
| Pittsburgh @ St. Louis | 7:45 PM | Busch Stadium |
| Houston @ Texas | 8:05 PM | Globe Life Field |
| San Diego @ Chi Cubs | 8:05 PM | Wrigley Field |
| Cleveland @ Colorado | 8:40 PM | Coors Field |
| Cincinnati @ Arizona | 9:40 PM | Chase Field |
| Kansas City @ SF Giants | 9:45 PM | Oracle Park |
| LA Angels @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Minnesota @ Seattle | 10:10 PM | T-Mobile Park |
| Wed Jun 15 | Time | Location |
| Miami @ Philadelphia | 1:05 PM | Citizens Bank Park |
| Chi Sox @ Detroit | 1:10 PM | Comerica Park |
| Houston @ Texas | 2:05 PM | Globe Life Field |
| Cincinnati @ Arizona | 3:40 PM | Chase Field |
| Kansas City @ SF Giants | 3:45 PM | Oracle Park |
| Minnesota @ Seattle | 4:10 PM | T-Mobile Park |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| Tampa Bay @ NY Yankees | 7:05 PM | Yankee Stadium |
| Baltimore @ Toronto | 7:07 PM | Rogers Centre |
| Oakland @ Boston | 7:10 PM | Fenway Park |
| Milwaukee @ NY Mets | 7:10 PM | Citi Field |
| Pittsburgh @ St. Louis | 7:45 PM | Busch Stadium |
| San Diego @ Chi Cubs | 8:05 PM | Wrigley Field |
| Cleveland @ Colorado | 8:40 PM | Coors Field |
| LA Angels @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Thu Jun 16 | Time | Location |
| Oakland @ Boston | 1:35 PM | Fenway Park |
| San Diego @ Chi Cubs | 2:20 PM | Wrigley Field |
| Baltimore @ Toronto | 3:07 PM | Rogers Centre |
| Cleveland @ Colorado | 3:10 PM | Coors Field |
| Philadelphia @ Washington | 7:05 PM | Nationals Park |
| Tampa Bay @ NY Yankees | 7:05 PM | Yankee Stadium |
| Milwaukee @ NY Mets | 7:10 PM | Citi Field |
| Texas @ Detroit | 7:10 PM | Comerica Park |
| LA Angels @ Seattle | 10:10 PM | T-Mobile Park |
| Fri Jun 17 | Time | Location |
| Philadelphia @ Washington | 1:05 PM | Nationals Park |
| Atlanta @ Chi Cubs | 2:20 PM | Wrigley Field |
| Tampa Bay @ Baltimore | 6:05 PM | Oriole Park at Camden Yards |
| Milwaukee @ Cincinnati | 6:40 PM | Great American Ball Park |
| Philadelphia @ Washington | 7:05 PM | Nationals Park |
| SF Giants @ Pittsburgh | 7:05 PM | PNC Park |
| NY Yankees @ Toronto | 7:07 PM | Rogers Centre |
| St. Louis @ Boston | 7:10 PM | Fenway Park |
| Texas @ Detroit | 7:10 PM | Comerica Park |
| Miami @ NY Mets | 7:10 PM | Citi Field |
| Chi Sox @ Houston | 8:10 PM | Minute Maid Park |
| San Diego @ Colorado | 8:40 PM | Coors Field |
| Kansas City @ Oakland | 9:40 PM | RingCentral Coliseum |
| Minnesota @ Arizona | 9:40 PM | Chase Field |
| LA Angels @ Seattle | 10:10 PM | T-Mobile Park |
| Cleveland @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sat Jun 18 | Time | Location |
| Atlanta @ Chi Cubs | 2:20 PM | Wrigley Field |
| NY Yankees @ Toronto | 3:07 PM | Rogers Centre |
| SF Giants @ Pittsburgh | 4:05 PM | PNC Park |
| Tampa Bay @ Baltimore | 4:05 PM | Oriole Park at Camden Yards |
| Kansas City @ Oakland | 4:07 PM | RingCentral Coliseum |
| Chi Sox @ Houston | 4:10 PM | Minute Maid Park |
| Miami @ NY Mets | 4:10 PM | Citi Field |
| Texas @ Detroit | 4:10 PM | Comerica Park |
| Milwaukee @ Cincinnati | 4:10 PM | Great American Ball Park |
| LA Angels @ Seattle | 4:10 PM | T-Mobile Park |
| Philadelphia @ Washington | 4:35 PM | Nationals Park |
| St. Louis @ Boston | 7:15 PM | Fenway Park |
| Cleveland @ LA Dodgers | 7:15 PM | Dodger Stadium |
| San Diego @ Colorado | 9:10 PM | Coors Field |
| LA Angels @ Seattle | 10:10 PM | T-Mobile Park |
| Minnesota @ Arizona | 10:10 PM | Chase Field |
| Sun Jun 19 | Time | Location |
| Philadelphia @ Washington | 12:05 PM | Nationals Park |
| St. Louis @ Boston | 1:35 PM | Fenway Park |
| SF Giants @ Pittsburgh | 1:35 PM | PNC Park |
| Tampa Bay @ Baltimore | 1:35 PM | Oriole Park at Camden Yards |
| NY Yankees @ Toronto | 1:37 PM | Rogers Centre |
| Milwaukee @ Cincinnati | 1:40 PM | Great American Ball Park |
| Miami @ NY Mets | 1:40 PM | Citi Field |
| Texas @ Detroit | 1:40 PM | Comerica Park |
| Atlanta @ Chi Cubs | 2:20 PM | Wrigley Field |
| San Diego @ Colorado | 3:10 PM | Coors Field |
| Kansas City @ Oakland | 4:07 PM | RingCentral Coliseum |
| Minnesota @ Arizona | 4:10 PM | Chase Field |
| Cleveland @ LA Dodgers | 4:10 PM | Dodger Stadium |
| LA Angels @ Seattle | 4:10 PM | T-Mobile Park |
| Chi Sox @ Houston | 7:08 PM | Minute Maid Park |
| Mon Jun 20 | Time | Location |
| Miami @ NY Mets | 1:10 PM | Citi Field |
| Chi Cubs @ Pittsburgh | 7:05 PM | PNC Park |
| Detroit @ Boston | 7:10 PM | Fenway Park |
| NY Yankees @ Tampa Bay | 7:10 PM | Tropicana Field |
| SF Giants @ Atlanta | 7:20 PM | Truist Park |
| Toronto @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| St. Louis @ Milwaukee | 8:10 PM | American Family Field |
| Kansas City @ LA Angels | 9:38 PM | Angel Stadium |
| Arizona @ San Diego | 9:40 PM | Petco Park |
| Tue Jun 21 | Time | Location |
| LA Dodgers @ Cincinnati | 6:40 PM | Great American Ball Park |
| Colorado @ Miami | 6:40 PM | loanDepot Park |
| Washington @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Chi Cubs @ Pittsburgh | 7:05 PM | PNC Park |
| Detroit @ Boston | 7:10 PM | Fenway Park |
| NY Yankees @ Tampa Bay | 7:10 PM | Tropicana Field |
| SF Giants @ Atlanta | 7:20 PM | Truist Park |
| Cleveland @ Minnesota | 7:40 PM | Target Field |
| Philadelphia @ Texas | 8:05 PM | Globe Life Field |
| Toronto @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| NY Mets @ Houston | 8:10 PM | Minute Maid Park |
| St. Louis @ Milwaukee | 8:10 PM | American Family Field |
| Kansas City @ LA Angels | 9:38 PM | Angel Stadium |
| Arizona @ San Diego | 9:40 PM | Petco Park |
| Seattle @ Oakland | 9:40 PM | RingCentral Coliseum |
| Wed Jun 22 | Time | Location |
| NY Mets @ Houston | 2:10 PM | Minute Maid Park |
| Toronto @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Philadelphia @ Texas | 4:05 PM | Globe Life Field |
| Arizona @ San Diego | 4:10 PM | Petco Park |
| LA Dodgers @ Cincinnati | 6:40 PM | Great American Ball Park |
| Colorado @ Miami | 6:40 PM | loanDepot Park |
| Washington @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Chi Cubs @ Pittsburgh | 7:05 PM | PNC Park |
| Detroit @ Boston | 7:10 PM | Fenway Park |
| NY Yankees @ Tampa Bay | 7:10 PM | Tropicana Field |
| SF Giants @ Atlanta | 7:20 PM | Truist Park |
| Cleveland @ Minnesota | 7:40 PM | Target Field |
| St. Louis @ Milwaukee | 8:10 PM | American Family Field |
| Seattle @ Oakland | 9:40 PM | RingCentral Coliseum |
| Kansas City @ LA Angels | 9:49 PM | Angel Stadium |
| Thu Jun 23 | Time | Location |
| Colorado @ Miami | 12:10 PM | loanDepot Park |
| SF Giants @ Atlanta | 12:20 PM | Truist Park |
| LA Dodgers @ Cincinnati | 12:35 PM | Great American Ball Park |
| Chi Cubs @ Pittsburgh | 12:35 PM | PNC Park |
| Cleveland @ Minnesota | 1:10 PM | Target Field |
| St. Louis @ Milwaukee | 2:10 PM | American Family Field |
| Seattle @ Oakland | 3:37 PM | RingCentral Coliseum |
| Houston @ NY Yankees | 7:05 PM | Yankee Stadium |
| Baltimore @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Philadelphia @ San Diego | 9:40 PM | Petco Park |
| Fri Jun 24 | Time | Location |
| NY Mets @ Miami | 6:40 PM | loanDepot Park |
| Houston @ NY Yankees | 7:05 PM | Yankee Stadium |
| Boston @ Cleveland | 7:10 PM | Progressive Field |
| Pittsburgh @ Tampa Bay | 7:10 PM | Tropicana Field |
| LA Dodgers @ Atlanta | 7:20 PM | Truist Park |
| Washington @ Texas | 8:05 PM | Globe Life Field |
| Oakland @ Kansas City | 8:10 PM | Kauffman Stadium |
| Colorado @ Minnesota | 8:10 PM | Target Field |
| Toronto @ Milwaukee | 8:10 PM | American Family Field |
| Baltimore @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Chi Cubs @ St. Louis | 8:15 PM | Busch Stadium |
| Seattle @ LA Angels | 9:38 PM | Angel Stadium |
| Philadelphia @ San Diego | 9:40 PM | Petco Park |
| Detroit @ Arizona | 9:40 PM | Chase Field |
| Cincinnati @ SF Giants | 10:15 PM | Oracle Park |
| Sat Jun 25 | Time | Location |
| Houston @ NY Yankees | 1:05 PM | Yankee Stadium |
| Pittsburgh @ Tampa Bay | 1:10 PM | Tropicana Field |
| Baltimore @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Chi Cubs @ St. Louis | 2:15 PM | Busch Stadium |
| Washington @ Texas | 4:05 PM | Globe Life Field |
| Oakland @ Kansas City | 4:10 PM | Kauffman Stadium |
| NY Mets @ Miami | 4:10 PM | loanDepot Park |
| Toronto @ Milwaukee | 4:10 PM | American Family Field |
| Boston @ Cleveland | 6:10 PM | Progressive Field |
| Colorado @ Minnesota | 7:15 PM | Target Field |
| Cincinnati @ SF Giants | 7:15 PM | Oracle Park |
| LA Dodgers @ Atlanta | 7:15 PM | Truist Park |
| Seattle @ LA Angels | 10:07 PM | Angel Stadium |
| Detroit @ Arizona | 10:10 PM | Chase Field |
| Philadelphia @ San Diego | 10:10 PM | Petco Park |
| Sun Jun 26 | Time | Location |
| NY Mets @ Miami | 12:05 PM | loanDepot Park |
| Houston @ NY Yankees | 1:35 PM | Yankee Stadium |
| Pittsburgh @ Tampa Bay | 1:40 PM | Tropicana Field |
| Boston @ Cleveland | 1:40 PM | Progressive Field |
| Oakland @ Kansas City | 2:10 PM | Kauffman Stadium |
| Colorado @ Minnesota | 2:10 PM | Target Field |
| Toronto @ Milwaukee | 2:10 PM | American Family Field |
| Baltimore @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Chi Cubs @ St. Louis | 2:15 PM | Busch Stadium |
| Washington @ Texas | 2:35 PM | Globe Life Field |
| Cincinnati @ SF Giants | 4:05 PM | Oracle Park |
| Seattle @ LA Angels | 4:07 PM | Angel Stadium |
| Detroit @ Arizona | 4:10 PM | Chase Field |
| Philadelphia @ San Diego | 4:10 PM | Petco Park |
| LA Dodgers @ Atlanta | 7:08 PM | Truist Park |
| Mon Jun 27 | Time | Location |
| Pittsburgh @ Washington | 7:05 PM | Nationals Park |
| Oakland @ NY Yankees | 7:05 PM | Yankee Stadium |
| Boston @ Toronto | 7:07 PM | Rogers Centre |
| Minnesota @ Cleveland | 7:10 PM | Progressive Field |
| Miami @ St. Louis | 7:45 PM | Busch Stadium |
| Texas @ Kansas City | 8:10 PM | Kauffman Stadium |
| LA Dodgers @ Colorado | 8:40 PM | Coors Field |
| Chi Sox @ LA Angels | 9:38 PM | Angel Stadium |
| Baltimore @ Seattle | 10:10 PM | T-Mobile Park |
| Tue Jun 28 | Time | Location |
| Minnesota @ Cleveland | 1:10 PM | Progressive Field |
| Pittsburgh @ Washington | 7:05 PM | Nationals Park |
| Oakland @ NY Yankees | 7:05 PM | Yankee Stadium |
| Atlanta @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Boston @ Toronto | 7:07 PM | Rogers Centre |
| Minnesota @ Cleveland | 7:10 PM | Progressive Field |
| Houston @ NY Mets | 7:10 PM | Citi Field |
| Milwaukee @ Tampa Bay | 7:10 PM | Tropicana Field |
| Miami @ St. Louis | 7:45 PM | Busch Stadium |
| Cincinnati @ Chi Cubs | 8:05 PM | Wrigley Field |
| Texas @ Kansas City | 8:10 PM | Kauffman Stadium |
| LA Dodgers @ Colorado | 8:40 PM | Coors Field |
| Chi Sox @ LA Angels | 9:38 PM | Angel Stadium |
| San Diego @ Arizona | 9:40 PM | Chase Field |
| Detroit @ SF Giants | 9:45 PM | Oracle Park |
| Baltimore @ Seattle | 10:10 PM | T-Mobile Park |
| Wed Jun 29 | Time | Location |
| Milwaukee @ Tampa Bay | 12:10 PM | Tropicana Field |
| Oakland @ NY Yankees | 1:05 PM | Yankee Stadium |
| Pittsburgh @ Washington | 1:05 PM | Nationals Park |
| Houston @ NY Mets | 1:10 PM | Citi Field |
| Texas @ Kansas City | 2:10 PM | Kauffman Stadium |
| San Diego @ Arizona | 3:40 PM | Chase Field |
| Detroit @ SF Giants | 3:45 PM | Oracle Park |
| Baltimore @ Seattle | 4:10 PM | T-Mobile Park |
| Atlanta @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Boston @ Toronto | 7:07 PM | Rogers Centre |
| Minnesota @ Cleveland | 7:10 PM | Progressive Field |
| Miami @ St. Louis | 7:45 PM | Busch Stadium |
| Cincinnati @ Chi Cubs | 8:05 PM | Wrigley Field |
| LA Dodgers @ Colorado | 8:40 PM | Coors Field |
| Chi Sox @ LA Angels | 9:38 PM | Angel Stadium |
| Thu Jun 30 | Time | Location |
| Minnesota @ Cleveland | 1:10 PM | Progressive Field |
| Atlanta @ Philadelphia | 6:05 PM | Citizens Bank Park |
| NY Yankees @ Houston | 6:10 PM | Minute Maid Park |
| Milwaukee @ Pittsburgh | 7:05 PM | PNC Park |
| Tampa Bay @ Toronto | 7:07 PM | Rogers Centre |
| Cincinnati @ Chi Cubs | 8:05 PM | Wrigley Field |
| San Diego @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Oakland @ Seattle | 10:10 PM | T-Mobile Park |
| Fri Jul 1 | Time | Location |
| Boston @ Chi Cubs | 2:20 PM | Wrigley Field |
| Tampa Bay @ Toronto | 3:07 PM | Rogers Centre |
| St. Louis @ Philadelphia | 6:05 PM | Citizens Bank Park |
| Miami @ Washington | 6:05 PM | Nationals Park |
| Atlanta @ Cincinnati | 6:40 PM | Great American Ball Park |
| Milwaukee @ Pittsburgh | 7:05 PM | PNC Park |
| Kansas City @ Detroit | 7:10 PM | Comerica Park |
| Texas @ NY Mets | 7:10 PM | Citi Field |
| Baltimore @ Minnesota | 8:10 PM | Target Field |
| Arizona @ Colorado | 8:10 PM | Coors Field |
| LA Angels @ Houston | 8:10 PM | Minute Maid Park |
| San Diego @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Oakland @ Seattle | 10:10 PM | T-Mobile Park |
| Chi Sox @ SF Giants | 10:15 PM | Oracle Park |
| Sat Jul 2 | Time | Location |
| Tampa Bay @ Toronto | 12:07 PM | Rogers Centre |
| NY Yankees @ Cleveland | 12:10 PM | Progressive Field |
| Baltimore @ Minnesota | 2:10 PM | Target Field |
| St. Louis @ Philadelphia | 4:05 PM | Citizens Bank Park |
| Milwaukee @ Pittsburgh | 4:05 PM | PNC Park |
| Chi Sox @ SF Giants | 4:05 PM | Oracle Park |
| Miami @ Washington | 4:05 PM | Nationals Park |
| Oakland @ Seattle | 4:10 PM | T-Mobile Park |
| Texas @ NY Mets | 4:10 PM | Citi Field |
| Atlanta @ Cincinnati | 4:10 PM | Great American Ball Park |
| LA Angels @ Houston | 4:10 PM | Minute Maid Park |
| Kansas City @ Detroit | 4:10 PM | Comerica Park |
| Tampa Bay @ Toronto | 6:07 PM | Rogers Centre |
| NY Yankees @ Cleveland | 6:10 PM | Progressive Field |
| San Diego @ LA Dodgers | 7:15 PM | Dodger Stadium |
| Boston @ Chi Cubs | 7:15 PM | Wrigley Field |
| Arizona @ Colorado | 9:10 PM | Coors Field |
| Sun Jul 3 | Time | Location |
| Kansas City @ Detroit | 12:05 PM | Comerica Park |
| Miami @ Washington | 1:35 PM | Nationals Park |
| Milwaukee @ Pittsburgh | 1:35 PM | PNC Park |
| Tampa Bay @ Toronto | 1:37 PM | Rogers Centre |
| NY Yankees @ Cleveland | 1:40 PM | Progressive Field |
| Atlanta @ Cincinnati | 1:40 PM | Great American Ball Park |
| Texas @ NY Mets | 1:40 PM | Citi Field |
| Baltimore @ Minnesota | 2:10 PM | Target Field |
| LA Angels @ Houston | 2:10 PM | Minute Maid Park |
| Boston @ Chi Cubs | 2:20 PM | Wrigley Field |
| Arizona @ Colorado | 3:10 PM | Coors Field |
| Chi Sox @ SF Giants | 4:05 PM | Oracle Park |
| San Diego @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Oakland @ Seattle | 4:10 PM | T-Mobile Park |
| St. Louis @ Philadelphia | 7:08 PM | Citizens Bank Park |
| Mon Jul 4 | Time | Location |
| Miami @ Washington | 11:05 AM | Nationals Park |
| Texas @ Baltimore | 1:05 PM | Oriole Park at Camden Yards |
| Cleveland @ Detroit | 1:10 PM | Comerica Park |
| Tampa Bay @ Boston | 1:35 PM | Fenway Park |
| Kansas City @ Houston | 4:10 PM | Minute Maid Park |
| Chi Cubs @ Milwaukee | 4:10 PM | American Family Field |
| SF Giants @ Arizona | 6:10 PM | Chase Field |
| NY Mets @ Cincinnati | 6:40 PM | Great American Ball Park |
| Seattle @ San Diego | 6:40 PM | Petco Park |
| Cleveland @ Detroit | 6:40 PM | Comerica Park |
| St. Louis @ Atlanta | 7:20 PM | Truist Park |
| Minnesota @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Toronto @ Oakland | 9:07 PM | RingCentral Coliseum |
| Colorado @ LA Dodgers | 9:10 PM | Dodger Stadium |
| Tue Jul 5 | Time | Location |
| Seattle @ San Diego | 4:10 PM | Petco Park |
| NY Mets @ Cincinnati | 6:40 PM | Great American Ball Park |
| LA Angels @ Miami | 6:40 PM | loanDepot Park |
| Texas @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Washington @ Philadelphia | 7:05 PM | Citizens Bank Park |
| NY Yankees @ Pittsburgh | 7:05 PM | PNC Park |
| Tampa Bay @ Boston | 7:10 PM | Fenway Park |
| Cleveland @ Detroit | 7:10 PM | Comerica Park |
| St. Louis @ Atlanta | 7:20 PM | Truist Park |
| Minnesota @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Kansas City @ Houston | 8:10 PM | Minute Maid Park |
| Chi Cubs @ Milwaukee | 8:10 PM | American Family Field |
| Toronto @ Oakland | 9:40 PM | RingCentral Coliseum |
| SF Giants @ Arizona | 9:40 PM | Chase Field |
| Colorado @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed Jul 6 | Time | Location |
| Cleveland @ Detroit | 1:10 PM | Comerica Park |
| Chi Cubs @ Milwaukee | 2:10 PM | American Family Field |
| Minnesota @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Toronto @ Oakland | 3:37 PM | RingCentral Coliseum |
| LA Angels @ Miami | 6:40 PM | loanDepot Park |
| NY Mets @ Cincinnati | 6:40 PM | Great American Ball Park |
| Texas @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Washington @ Philadelphia | 7:05 PM | Citizens Bank Park |
| NY Yankees @ Pittsburgh | 7:05 PM | PNC Park |
| Tampa Bay @ Boston | 7:10 PM | Fenway Park |
| St. Louis @ Atlanta | 7:20 PM | Truist Park |
| Kansas City @ Houston | 8:10 PM | Minute Maid Park |
| SF Giants @ Arizona | 9:40 PM | Chase Field |
| Colorado @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Thu Jul 7 | Time | Location |
| Kansas City @ Houston | 2:10 PM | Minute Maid Park |
| Pittsburgh @ Cincinnati | 2:10 PM | Great American Ball Park |
| Washington @ Philadelphia | 4:05 PM | Citizens Bank Park |
| LA Angels @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| NY Yankees @ Boston | 7:10 PM | Fenway Park |
| Miami @ NY Mets | 7:10 PM | Citi Field |
| Pittsburgh @ Cincinnati | 7:10 PM | Great American Ball Park |
| St. Louis @ Atlanta | 7:20 PM | Truist Park |
| Detroit @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Colorado @ Arizona | 9:40 PM | Chase Field |
| SF Giants @ San Diego | 9:40 PM | Petco Park |
| Chi Cubs @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Toronto @ Seattle | 10:10 PM | T-Mobile Park |
| Fri Jul 8 | Time | Location |
| Tampa Bay @ Cincinnati | 6:40 PM | Great American Ball Park |
| LA Angels @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Miami @ NY Mets | 7:10 PM | Citi Field |
| NY Yankees @ Boston | 7:10 PM | Fenway Park |
| Washington @ Atlanta | 7:20 PM | Truist Park |
| Minnesota @ Texas | 8:05 PM | Globe Life Field |
| Detroit @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Cleveland @ Kansas City | 8:10 PM | Kauffman Stadium |
| Pittsburgh @ Milwaukee | 8:10 PM | American Family Field |
| Philadelphia @ St. Louis | 8:15 PM | Busch Stadium |
| Houston @ Oakland | 9:40 PM | RingCentral Coliseum |
| SF Giants @ San Diego | 9:40 PM | Petco Park |
| Colorado @ Arizona | 9:40 PM | Chase Field |
| Chi Cubs @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Toronto @ Seattle | 10:10 PM | T-Mobile Park |
| Sat Jul 9 | Time | Location |
| Detroit @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Philadelphia @ St. Louis | 2:15 PM | Busch Stadium |
| LA Angels @ Baltimore | 4:05 PM | Oriole Park at Camden Yards |
| Minnesota @ Texas | 4:05 PM | Globe Life Field |
| Houston @ Oakland | 4:07 PM | RingCentral Coliseum |
| Pittsburgh @ Milwaukee | 4:10 PM | American Family Field |
| Colorado @ Arizona | 4:10 PM | Chase Field |
| Cleveland @ Kansas City | 4:10 PM | Kauffman Stadium |
| Washington @ Atlanta | 4:10 PM | Truist Park |
| Tampa Bay @ Cincinnati | 4:10 PM | Great American Ball Park |
| Miami @ NY Mets | 4:10 PM | Citi Field |
| NY Yankees @ Boston | 7:15 PM | Fenway Park |
| SF Giants @ San Diego | 7:15 PM | Petco Park |
| Chi Cubs @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Toronto @ Seattle | 10:10 PM | T-Mobile Park |
| Sun Jul 10 | Time | Location |
| LA Angels @ Baltimore | 12:05 PM | Oriole Park at Camden Yards |
| Washington @ Atlanta | 1:35 PM | Truist Park |
| Miami @ NY Mets | 1:40 PM | Citi Field |
| Tampa Bay @ Cincinnati | 1:40 PM | Great American Ball Park |
| Cleveland @ Kansas City | 2:10 PM | Kauffman Stadium |
| Pittsburgh @ Milwaukee | 2:10 PM | American Family Field |
| Detroit @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Philadelphia @ St. Louis | 2:15 PM | Busch Stadium |
| Minnesota @ Texas | 2:35 PM | Globe Life Field |
| Houston @ Oakland | 4:07 PM | RingCentral Coliseum |
| SF Giants @ San Diego | 4:10 PM | Petco Park |
| Toronto @ Seattle | 4:10 PM | T-Mobile Park |
| Chi Cubs @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Colorado @ Arizona | 4:10 PM | Chase Field |
| NY Yankees @ Boston | 7:08 PM | Fenway Park |
| Mon Jul 11 | Time | Location |
| Detroit @ Kansas City | 2:10 PM | Kauffman Stadium |
| Pittsburgh @ Miami | 6:40 PM | loanDepot Park |
| Boston @ Tampa Bay | 7:10 PM | Tropicana Field |
| Chi Sox @ Cleveland | 7:10 PM | Progressive Field |
| Philadelphia @ St. Louis | 7:15 PM | Busch Stadium |
| NY Mets @ Atlanta | 7:20 PM | Truist Park |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| Detroit @ Kansas City | 8:10 PM | Kauffman Stadium |
| San Diego @ Colorado | 8:40 PM | Coors Field |
| Arizona @ SF Giants | 9:45 PM | Oracle Park |
| Tue Jul 12 | Time | Location |
| Chi Sox @ Cleveland | 1:10 PM | Progressive Field |
| Pittsburgh @ Miami | 6:40 PM | loanDepot Park |
| Cincinnati @ NY Yankees | 7:05 PM | Yankee Stadium |
| Philadelphia @ Toronto | 7:07 PM | Rogers Centre |
| Boston @ Tampa Bay | 7:10 PM | Tropicana Field |
| Chi Sox @ Cleveland | 7:10 PM | Progressive Field |
| NY Mets @ Atlanta | 7:20 PM | Truist Park |
| Milwaukee @ Minnesota | 7:40 PM | Target Field |
| LA Dodgers @ St. Louis | 7:45 PM | Busch Stadium |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| Baltimore @ Chi Cubs | 8:05 PM | Wrigley Field |
| Detroit @ Kansas City | 8:10 PM | Kauffman Stadium |
| San Diego @ Colorado | 8:40 PM | Coors Field |
| Houston @ LA Angels | 9:38 PM | Angel Stadium |
| Arizona @ SF Giants | 9:45 PM | Oracle Park |
| Wed Jul 13 | Time | Location |
| Seattle @ Washington | 12:05 PM | Nationals Park |
| NY Mets @ Atlanta | 12:20 PM | Truist Park |
| Milwaukee @ Minnesota | 1:10 PM | Target Field |
| Detroit @ Kansas City | 2:10 PM | Kauffman Stadium |
| Arizona @ SF Giants | 3:45 PM | Oracle Park |
| Seattle @ Washington | 6:05 PM | Nationals Park |
| Pittsburgh @ Miami | 6:40 PM | loanDepot Park |
| Cincinnati @ NY Yankees | 7:05 PM | Yankee Stadium |
| Philadelphia @ Toronto | 7:07 PM | Rogers Centre |
| Chi Sox @ Cleveland | 7:10 PM | Progressive Field |
| Boston @ Tampa Bay | 7:10 PM | Tropicana Field |
| LA Dodgers @ St. Louis | 7:45 PM | Busch Stadium |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| Baltimore @ Chi Cubs | 8:05 PM | Wrigley Field |
| San Diego @ Colorado | 8:40 PM | Coors Field |
| Houston @ LA Angels | 9:38 PM | Angel Stadium |
| Thu Jul 14 | Time | Location |
| Pittsburgh @ Miami | 12:10 PM | loanDepot Park |
| San Diego @ Colorado | 3:10 PM | Coors Field |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| Cincinnati @ NY Yankees | 7:05 PM | Yankee Stadium |
| Kansas City @ Toronto | 7:07 PM | Rogers Centre |
| Boston @ Tampa Bay | 7:10 PM | Tropicana Field |
| Detroit @ Cleveland | 7:10 PM | Progressive Field |
| LA Dodgers @ St. Louis | 7:15 PM | Busch Stadium |
| Chi Sox @ Minnesota | 7:40 PM | Target Field |
| NY Mets @ Chi Cubs | 8:05 PM | Wrigley Field |
| Seattle @ Texas | 8:05 PM | Globe Life Field |
| Houston @ LA Angels | 8:07 PM | Angel Stadium |
| Milwaukee @ SF Giants | 9:45 PM | Oracle Park |
| Fri Jul 15 | Time | Location |
| Philadelphia @ Miami | 6:40 PM | loanDepot Park |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| Boston @ NY Yankees | 7:05 PM | Yankee Stadium |
| Kansas City @ Toronto | 7:07 PM | Rogers Centre |
| Baltimore @ Tampa Bay | 7:10 PM | Tropicana Field |
| Detroit @ Cleveland | 7:10 PM | Progressive Field |
| Seattle @ Texas | 8:05 PM | Globe Life Field |
| Oakland @ Houston | 8:10 PM | Minute Maid Park |
| Chi Sox @ Minnesota | 8:10 PM | Target Field |
| Cincinnati @ St. Louis | 8:15 PM | Busch Stadium |
| Pittsburgh @ Colorado | 8:40 PM | Coors Field |
| LA Dodgers @ LA Angels | 9:38 PM | Angel Stadium |
| Arizona @ San Diego | 9:40 PM | Petco Park |
| Milwaukee @ SF Giants | 10:15 PM | Oracle Park |
| Sat Jul 16 | Time | Location |
| Chi Sox @ Minnesota | 2:10 PM | Target Field |
| Cincinnati @ St. Louis | 2:15 PM | Busch Stadium |
| NY Mets @ Chi Cubs | 2:20 PM | Wrigley Field |
| Kansas City @ Toronto | 3:07 PM | Rogers Centre |
| Pittsburgh @ Colorado | 3:10 PM | Coors Field |
| Atlanta @ Washington | 4:05 PM | Nationals Park |
| Seattle @ Texas | 4:05 PM | Globe Life Field |
| Baltimore @ Tampa Bay | 4:10 PM | Tropicana Field |
| Oakland @ Houston | 4:10 PM | Minute Maid Park |
| Philadelphia @ Miami | 4:10 PM | loanDepot Park |
| Detroit @ Cleveland | 4:10 PM | Progressive Field |
| Boston @ NY Yankees | 7:15 PM | Yankee Stadium |
| Milwaukee @ SF Giants | 7:15 PM | Oracle Park |
| NY Mets @ Chi Cubs | 8:05 PM | Wrigley Field |
| Arizona @ San Diego | 8:40 PM | Petco Park |
| LA Dodgers @ LA Angels | 10:07 PM | Angel Stadium |
| Sun Jul 17 | Time | Location |
| Kansas City @ Toronto | 12:05 PM | Rogers Centre |
| Atlanta @ Washington | 1:35 PM | Nationals Park |
| Boston @ NY Yankees | 1:35 PM | Yankee Stadium |
| Baltimore @ Tampa Bay | 1:40 PM | Tropicana Field |
| Philadelphia @ Miami | 1:40 PM | loanDepot Park |
| Oakland @ Houston | 2:10 PM | Minute Maid Park |
| Chi Sox @ Minnesota | 2:10 PM | Target Field |
| NY Mets @ Chi Cubs | 2:20 PM | Wrigley Field |
| Seattle @ Texas | 2:35 PM | Globe Life Field |
| Pittsburgh @ Colorado | 3:10 PM | Coors Field |
| Milwaukee @ SF Giants | 4:05 PM | Oracle Park |
| Arizona @ San Diego | 4:10 PM | Petco Park |
| Thu Jul 21 | Time | Location |
| Texas @ Miami | 1:10 PM | loanDepot Park |
| NY Yankees @ Houston | 1:10 PM | Minute Maid Park |
| Detroit @ Oakland | 3:37 PM | RingCentral Coliseum |
| Detroit @ Oakland | 6:37 PM | RingCentral Coliseum |
| NY Yankees @ Houston | 6:40 PM | Minute Maid Park |
| SF Giants @ LA Dodgers | 10:09 PM | Dodger Stadium |
| Fri Jul 22 | Time | Location |
| St. Louis @ Cincinnati | 6:40 PM | Great American Ball Park |
| Chi Cubs @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Miami @ Pittsburgh | 7:05 PM | PNC Park |
| NY Yankees @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Toronto @ Boston | 7:10 PM | Fenway Park |
| San Diego @ NY Mets | 7:10 PM | Citi Field |
| LA Angels @ Atlanta | 7:20 PM | Truist Park |
| Cleveland @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Tampa Bay @ Kansas City | 8:10 PM | Kauffman Stadium |
| Colorado @ Milwaukee | 8:10 PM | American Family Field |
| Washington @ Arizona | 9:40 PM | Chase Field |
| Texas @ Oakland | 9:40 PM | RingCentral Coliseum |
| Houston @ Seattle | 10:10 PM | T-Mobile Park |
| SF Giants @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sat Jul 23 | Time | Location |
| Cleveland @ Chi Sox | 1:10 PM | Guaranteed Rate Field |
| Houston @ Seattle | 4:10 PM | T-Mobile Park |
| Toronto @ Boston | 4:10 PM | Fenway Park |
| Chi Cubs @ Philadelphia | 6:05 PM | Citizens Bank Park |
| Minnesota @ Detroit | 6:10 PM | Comerica Park |
| St. Louis @ Cincinnati | 6:40 PM | Great American Ball Park |
| Miami @ Pittsburgh | 7:05 PM | PNC Park |
| NY Yankees @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Tampa Bay @ Kansas City | 7:10 PM | Kauffman Stadium |
| Colorado @ Milwaukee | 7:10 PM | American Family Field |
| San Diego @ NY Mets | 7:10 PM | Citi Field |
| SF Giants @ LA Dodgers | 7:15 PM | Dodger Stadium |
| Cleveland @ Chi Sox | 7:15 PM | Guaranteed Rate Field |
| LA Angels @ Atlanta | 7:20 PM | Truist Park |
| Washington @ Arizona | 8:10 PM | Chase Field |
| Texas @ Oakland | 9:07 PM | RingCentral Coliseum |
| Sun Jul 24 | Time | Location |
| Chi Cubs @ Philadelphia | 12:05 PM | Citizens Bank Park |
| Toronto @ Boston | 1:35 PM | Fenway Park |
| LA Angels @ Atlanta | 1:35 PM | Truist Park |
| Miami @ Pittsburgh | 1:35 PM | PNC Park |
| NY Yankees @ Baltimore | 1:35 PM | Oriole Park at Camden Yards |
| Minnesota @ Detroit | 1:40 PM | Comerica Park |
| St. Louis @ Cincinnati | 1:40 PM | Great American Ball Park |
| Tampa Bay @ Kansas City | 2:10 PM | Kauffman Stadium |
| Cleveland @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Colorado @ Milwaukee | 2:10 PM | American Family Field |
| Texas @ Oakland | 4:07 PM | RingCentral Coliseum |
| Houston @ Seattle | 4:10 PM | T-Mobile Park |
| SF Giants @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Washington @ Arizona | 4:10 PM | Chase Field |
| San Diego @ NY Mets | 7:08 PM | Citi Field |
| Mon Jul 25 | Time | Location |
| Miami @ Cincinnati | 6:40 PM | Great American Ball Park |
| Tampa Bay @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Atlanta @ Philadelphia | 7:05 PM | Citizens Bank Park |
| San Diego @ Detroit | 7:10 PM | Comerica Park |
| Cleveland @ Boston | 7:10 PM | Fenway Park |
| Pittsburgh @ Chi Cubs | 8:05 PM | Wrigley Field |
| LA Angels @ Kansas City | 8:10 PM | Kauffman Stadium |
| Colorado @ Milwaukee | 8:10 PM | American Family Field |
| Houston @ Oakland | 9:40 PM | RingCentral Coliseum |
| SF Giants @ Arizona | 9:40 PM | Chase Field |
| Texas @ Seattle | 10:10 PM | T-Mobile Park |
| Washington @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Tue Jul 26 | Time | Location |
| Pittsburgh @ Chi Cubs | 2:20 PM | Wrigley Field |
| Miami @ Cincinnati | 6:40 PM | Great American Ball Park |
| Tampa Bay @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Atlanta @ Philadelphia | 7:05 PM | Citizens Bank Park |
| St. Louis @ Toronto | 7:07 PM | Rogers Centre |
| San Diego @ Detroit | 7:10 PM | Comerica Park |
| Cleveland @ Boston | 7:10 PM | Fenway Park |
| NY Yankees @ NY Mets | 7:10 PM | Citi Field |
| LA Angels @ Kansas City | 8:10 PM | Kauffman Stadium |
| Minnesota @ Milwaukee | 8:10 PM | American Family Field |
| Chi Sox @ Colorado | 8:40 PM | Coors Field |
| SF Giants @ Arizona | 9:40 PM | Chase Field |
| Houston @ Oakland | 9:40 PM | RingCentral Coliseum |
| Texas @ Seattle | 10:10 PM | T-Mobile Park |
| Washington @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed Jul 27 | Time | Location |
| Atlanta @ Philadelphia | 12:35 PM | Citizens Bank Park |
| San Diego @ Detroit | 1:10 PM | Comerica Park |
| LA Angels @ Kansas City | 2:10 PM | Kauffman Stadium |
| Minnesota @ Milwaukee | 2:10 PM | American Family Field |
| Washington @ LA Dodgers | 3:10 PM | Dodger Stadium |
| Chi Sox @ Colorado | 3:10 PM | Coors Field |
| Houston @ Oakland | 3:37 PM | RingCentral Coliseum |
| SF Giants @ Arizona | 3:40 PM | Chase Field |
| Texas @ Seattle | 3:40 PM | T-Mobile Park |
| Miami @ Cincinnati | 6:40 PM | Great American Ball Park |
| Tampa Bay @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| St. Louis @ Toronto | 7:07 PM | Rogers Centre |
| NY Yankees @ NY Mets | 7:10 PM | Citi Field |
| Cleveland @ Boston | 7:10 PM | Fenway Park |
| Thu Jul 28 | Time | Location |
| Tampa Bay @ Baltimore | 12:35 PM | Oriole Park at Camden Yards |
| Miami @ Cincinnati | 12:35 PM | Great American Ball Park |
| Kansas City @ NY Yankees | 7:05 PM | Yankee Stadium |
| Philadelphia @ Pittsburgh | 7:05 PM | PNC Park |
| Detroit @ Toronto | 7:07 PM | Rogers Centre |
| Cleveland @ Boston | 7:10 PM | Fenway Park |
| Seattle @ Houston | 8:10 PM | Minute Maid Park |
| LA Dodgers @ Colorado | 8:40 PM | Coors Field |
| Texas @ LA Angels | 9:38 PM | Angel Stadium |
| Chi Cubs @ SF Giants | 9:45 PM | Oracle Park |
| Fri Jul 29 | Time | Location |
| NY Mets @ Miami | 6:40 PM | loanDepot Park |
| Baltimore @ Cincinnati | 6:40 PM | Great American Ball Park |
| St. Louis @ Washington | 7:05 PM | Nationals Park |
| Philadelphia @ Pittsburgh | 7:05 PM | PNC Park |
| Kansas City @ NY Yankees | 7:05 PM | Yankee Stadium |
| Detroit @ Toronto | 7:07 PM | Rogers Centre |
| Cleveland @ Tampa Bay | 7:10 PM | Tropicana Field |
| Milwaukee @ Boston | 7:10 PM | Fenway Park |
| Arizona @ Atlanta | 7:20 PM | Truist Park |
| Oakland @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Seattle @ Houston | 8:10 PM | Minute Maid Park |
| LA Dodgers @ Colorado | 8:40 PM | Coors Field |
| Texas @ LA Angels | 9:38 PM | Angel Stadium |
| Minnesota @ San Diego | 9:40 PM | Petco Park |
| Chi Cubs @ SF Giants | 10:15 PM | Oracle Park |
| Sat Jul 30 | Time | Location |
| Cleveland @ Tampa Bay | 1:10 PM | Tropicana Field |
| Kansas City @ NY Yankees | 2:05 PM | Yankee Stadium |
| Detroit @ Toronto | 3:07 PM | Rogers Centre |
| Milwaukee @ Boston | 4:10 PM | Fenway Park |
| NY Mets @ Miami | 6:10 PM | loanDepot Park |
| Baltimore @ Cincinnati | 6:40 PM | Great American Ball Park |
| Seattle @ Houston | 7:10 PM | Minute Maid Park |
| St. Louis @ Washington | 7:15 PM | Nationals Park |
| Philadelphia @ Pittsburgh | 7:15 PM | PNC Park |
| Oakland @ Chi Sox | 7:15 PM | Guaranteed Rate Field |
| Minnesota @ San Diego | 7:15 PM | Petco Park |
| Arizona @ Atlanta | 7:20 PM | Truist Park |
| LA Dodgers @ Colorado | 8:10 PM | Coors Field |
| Chi Cubs @ SF Giants | 9:05 PM | Oracle Park |
| Texas @ LA Angels | 9:07 PM | Angel Stadium |
| Sun Jul 31 | Time | Location |
| Detroit @ Toronto | 12:05 PM | Rogers Centre |
| St. Louis @ Washington | 1:35 PM | Nationals Park |
| Philadelphia @ Pittsburgh | 1:35 PM | PNC Park |
| Arizona @ Atlanta | 1:35 PM | Truist Park |
| Kansas City @ NY Yankees | 1:35 PM | Yankee Stadium |
| Milwaukee @ Boston | 1:35 PM | Fenway Park |
| Cleveland @ Tampa Bay | 1:40 PM | Tropicana Field |
| NY Mets @ Miami | 1:40 PM | loanDepot Park |
| Baltimore @ Cincinnati | 1:40 PM | Great American Ball Park |
| Seattle @ Houston | 2:10 PM | Minute Maid Park |
| Oakland @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| LA Dodgers @ Colorado | 3:10 PM | Coors Field |
| Texas @ LA Angels | 4:07 PM | Angel Stadium |
| Minnesota @ San Diego | 4:10 PM | Petco Park |
| Chi Cubs @ SF Giants | 7:08 PM | Oracle Park |
| Mon Aug 1 | Time | Location |
| Cincinnati @ Miami | 6:40 PM | loanDepot Park |
| NY Mets @ Washington | 7:05 PM | Nationals Park |
| Seattle @ NY Yankees | 7:05 PM | Yankee Stadium |
| Arizona @ Cleveland | 7:10 PM | Progressive Field |
| Detroit @ Minnesota | 7:40 PM | Target Field |
| Baltimore @ Texas | 8:05 PM | Globe Life Field |
| Kansas City @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Boston @ Houston | 8:10 PM | Minute Maid Park |
| Colorado @ San Diego | 9:40 PM | Petco Park |
| LA Dodgers @ SF Giants | 9:45 PM | Oracle Park |
| Tue Aug 2 | Time | Location |
| Colorado @ San Diego | 4:10 PM | Petco Park |
| Cincinnati @ Miami | 6:40 PM | loanDepot Park |
| NY Mets @ Washington | 7:05 PM | Nationals Park |
| Seattle @ NY Yankees | 7:05 PM | Yankee Stadium |
| Milwaukee @ Pittsburgh | 7:05 PM | PNC Park |
| Toronto @ Tampa Bay | 7:10 PM | Tropicana Field |
| Arizona @ Cleveland | 7:10 PM | Progressive Field |
| Philadelphia @ Atlanta | 7:20 PM | Truist Park |
| Detroit @ Minnesota | 7:40 PM | Target Field |
| Chi Cubs @ St. Louis | 7:45 PM | Busch Stadium |
| Baltimore @ Texas | 8:05 PM | Globe Life Field |
| Kansas City @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Boston @ Houston | 8:10 PM | Minute Maid Park |
| Oakland @ LA Angels | 9:38 PM | Angel Stadium |
| LA Dodgers @ SF Giants | 9:45 PM | Oracle Park |
| Colorado @ San Diego | 10:10 PM | Petco Park |
| Wed Aug 3 | Time | Location |
| Toronto @ Tampa Bay | 12:10 PM | Tropicana Field |
| Philadelphia @ Atlanta | 12:20 PM | Truist Park |
| Seattle @ NY Yankees | 1:05 PM | Yankee Stadium |
| Arizona @ Cleveland | 1:10 PM | Progressive Field |
| Detroit @ Minnesota | 1:10 PM | Target Field |
| Baltimore @ Texas | 2:05 PM | Globe Life Field |
| Kansas City @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Boston @ Houston | 2:10 PM | Minute Maid Park |
| NY Mets @ Washington | 4:05 PM | Nationals Park |
| Cincinnati @ Miami | 6:40 PM | loanDepot Park |
| Milwaukee @ Pittsburgh | 7:05 PM | PNC Park |
| Oakland @ LA Angels | 9:38 PM | Angel Stadium |
| Colorado @ San Diego | 9:40 PM | Petco Park |
| LA Dodgers @ SF Giants | 9:45 PM | Oracle Park |
| Thu Aug 4 | Time | Location |
| Milwaukee @ Pittsburgh | 12:35 PM | PNC Park |
| Chi Cubs @ St. Louis | 1:15 PM | Busch Stadium |
| LA Dodgers @ SF Giants | 3:45 PM | Oracle Park |
| Oakland @ LA Angels | 4:07 PM | Angel Stadium |
| Colorado @ San Diego | 4:10 PM | Petco Park |
| Washington @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Atlanta @ NY Mets | 7:10 PM | Citi Field |
| Houston @ Cleveland | 7:10 PM | Progressive Field |
| Tampa Bay @ Detroit | 7:10 PM | Comerica Park |
| Toronto @ Minnesota | 7:40 PM | Target Field |
| Chi Cubs @ St. Louis | 7:45 PM | Busch Stadium |
| Chi Sox @ Texas | 8:05 PM | Globe Life Field |
| Boston @ Kansas City | 8:10 PM | Kauffman Stadium |
| Fri Aug 5 | Time | Location |
| Miami @ Chi Cubs | 2:20 PM | Wrigley Field |
| Washington @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Pittsburgh @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Tampa Bay @ Detroit | 7:10 PM | Comerica Park |
| Atlanta @ NY Mets | 7:10 PM | Citi Field |
| Houston @ Cleveland | 7:10 PM | Progressive Field |
| Chi Sox @ Texas | 8:05 PM | Globe Life Field |
| Boston @ Kansas City | 8:10 PM | Kauffman Stadium |
| Toronto @ Minnesota | 8:10 PM | Target Field |
| Cincinnati @ Milwaukee | 8:10 PM | American Family Field |
| NY Yankees @ St. Louis | 8:15 PM | Busch Stadium |
| Colorado @ Arizona | 9:40 PM | Chase Field |
| San Diego @ LA Dodgers | 10:10 PM | Dodger Stadium |
| LA Angels @ Seattle | 10:10 PM | T-Mobile Park |
| Sat Aug 6 | Time | Location |
| Atlanta @ NY Mets | 1:10 PM | Citi Field |
| Miami @ Chi Cubs | 2:20 PM | Wrigley Field |
| LA Angels @ Seattle | 4:10 PM | T-Mobile Park |
| Pittsburgh @ Baltimore | 5:05 PM | Oriole Park at Camden Yards |
| Washington @ Philadelphia | 6:05 PM | Citizens Bank Park |
| Tampa Bay @ Detroit | 6:10 PM | Comerica Park |
| Houston @ Cleveland | 6:10 PM | Progressive Field |
| Chi Sox @ Texas | 7:05 PM | Globe Life Field |
| SF Giants @ Oakland | 7:07 PM | RingCentral Coliseum |
| Boston @ Kansas City | 7:10 PM | Kauffman Stadium |
| Toronto @ Minnesota | 7:10 PM | Target Field |
| Atlanta @ NY Mets | 7:10 PM | Citi Field |
| Cincinnati @ Milwaukee | 7:15 PM | American Family Field |
| NY Yankees @ St. Louis | 7:15 PM | Busch Stadium |
| Colorado @ Arizona | 8:10 PM | Chase Field |
| San Diego @ LA Dodgers | 9:10 PM | Dodger Stadium |
| LA Angels @ Seattle | 10:10 PM | T-Mobile Park |
| Sun Aug 7 | Time | Location |
| Houston @ Cleveland | 12:05 PM | Progressive Field |
| Pittsburgh @ Baltimore | 1:35 PM | Oriole Park at Camden Yards |
| Washington @ Philadelphia | 1:35 PM | Citizens Bank Park |
| Tampa Bay @ Detroit | 1:40 PM | Comerica Park |
| Boston @ Kansas City | 2:10 PM | Kauffman Stadium |
| Toronto @ Minnesota | 2:10 PM | Target Field |
| Cincinnati @ Milwaukee | 2:10 PM | American Family Field |
| NY Yankees @ St. Louis | 2:15 PM | Busch Stadium |
| Miami @ Chi Cubs | 2:20 PM | Wrigley Field |
| Chi Sox @ Texas | 2:35 PM | Globe Life Field |
| SF Giants @ Oakland | 4:07 PM | RingCentral Coliseum |
| Atlanta @ NY Mets | 4:10 PM | Citi Field |
| LA Angels @ Seattle | 4:10 PM | T-Mobile Park |
| Colorado @ Arizona | 4:10 PM | Chase Field |
| San Diego @ LA Dodgers | 7:08 PM | Dodger Stadium |
| Mon Aug 8 | Time | Location |
| Toronto @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Cincinnati @ NY Mets | 7:10 PM | Citi Field |
| Washington @ Chi Cubs | 8:05 PM | Wrigley Field |
| LA Angels @ Oakland | 9:40 PM | RingCentral Coliseum |
| Pittsburgh @ Arizona | 9:40 PM | Chase Field |
| SF Giants @ San Diego | 9:40 PM | Petco Park |
| NY Yankees @ Seattle | 10:10 PM | T-Mobile Park |
| Tue Aug 9 | Time | Location |
| Chi Sox @ Kansas City | 4:10 PM | Kauffman Stadium |
| Toronto @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Miami @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Atlanta @ Boston | 7:10 PM | Fenway Park |
| Cleveland @ Detroit | 7:10 PM | Comerica Park |
| Cincinnati @ NY Mets | 7:10 PM | Citi Field |
| Chi Sox @ Kansas City | 7:10 PM | Kauffman Stadium |
| Washington @ Chi Cubs | 8:05 PM | Wrigley Field |
| Tampa Bay @ Milwaukee | 8:10 PM | American Family Field |
| Texas @ Houston | 8:10 PM | Minute Maid Park |
| St. Louis @ Colorado | 8:40 PM | Coors Field |
| LA Angels @ Oakland | 9:40 PM | RingCentral Coliseum |
| Pittsburgh @ Arizona | 9:40 PM | Chase Field |
| SF Giants @ San Diego | 9:40 PM | Petco Park |
| Minnesota @ LA Dodgers | 10:10 PM | Dodger Stadium |
| NY Yankees @ Seattle | 10:10 PM | T-Mobile Park |
| Wed Aug 10 | Time | Location |
| Cincinnati @ NY Mets | 1:10 PM | Citi Field |
| Tampa Bay @ Milwaukee | 2:10 PM | American Family Field |
| Washington @ Chi Cubs | 2:20 PM | Wrigley Field |
| LA Angels @ Oakland | 3:37 PM | RingCentral Coliseum |
| SF Giants @ San Diego | 4:10 PM | Petco Park |
| NY Yankees @ Seattle | 4:10 PM | T-Mobile Park |
| Miami @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Atlanta @ Boston | 7:10 PM | Fenway Park |
| Cleveland @ Detroit | 7:10 PM | Comerica Park |
| Texas @ Houston | 8:10 PM | Minute Maid Park |
| Chi Sox @ Kansas City | 8:10 PM | Kauffman Stadium |
| St. Louis @ Colorado | 8:40 PM | Coors Field |
| Pittsburgh @ Arizona | 9:40 PM | Chase Field |
| Minnesota @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Thu Aug 11 | Time | Location |
| Miami @ Philadelphia | 1:05 PM | Citizens Bank Park |
| Cleveland @ Detroit | 1:10 PM | Comerica Park |
| Texas @ Houston | 2:10 PM | Minute Maid Park |
| Chi Sox @ Kansas City | 2:10 PM | Kauffman Stadium |
| St. Louis @ Colorado | 3:10 PM | Coors Field |
| Pittsburgh @ Arizona | 3:40 PM | Chase Field |
| Baltimore @ Boston | 7:10 PM | Fenway Park |
| Chi Cubs vs. Cincinnati | 7:15 PM | Field of Dreams |
| Fri Aug 12 | Time | Location |
| Atlanta @ Miami | 6:40 PM | loanDepot Park |
| San Diego @ Washington | 7:05 PM | Nationals Park |
| Cleveland @ Toronto | 7:07 PM | Rogers Centre |
| Baltimore @ Tampa Bay | 7:10 PM | Tropicana Field |
| Philadelphia @ NY Mets | 7:10 PM | Citi Field |
| Detroit @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| NY Yankees @ Boston | 7:10 PM | Fenway Park |
| Seattle @ Texas | 8:05 PM | Globe Life Field |
| LA Dodgers @ Kansas City | 8:10 PM | Kauffman Stadium |
| Oakland @ Houston | 8:10 PM | Minute Maid Park |
| Milwaukee @ St. Louis | 8:15 PM | Busch Stadium |
| Arizona @ Colorado | 8:40 PM | Coors Field |
| Minnesota @ LA Angels | 9:38 PM | Angel Stadium |
| Pittsburgh @ SF Giants | 10:15 PM | Oracle Park |
| Sat Aug 13 | Time | Location |
| Atlanta @ Miami | 1:10 PM | loanDepot Park |
| Cleveland @ Toronto | 3:07 PM | Rogers Centre |
| Baltimore @ Tampa Bay | 4:10 PM | Tropicana Field |
| Chi Cubs @ Cincinnati | 6:40 PM | Great American Ball Park |
| San Diego @ Washington | 7:05 PM | Nationals Park |
| LA Dodgers @ Kansas City | 7:10 PM | Kauffman Stadium |
| Oakland @ Houston | 7:10 PM | Minute Maid Park |
| Philadelphia @ NY Mets | 7:10 PM | Citi Field |
| Detroit @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| Atlanta @ Miami | 7:10 PM | loanDepot Park |
| NY Yankees @ Boston | 7:15 PM | Fenway Park |
| Milwaukee @ St. Louis | 7:15 PM | Busch Stadium |
| Seattle @ Texas | 7:15 PM | Globe Life Field |
| Arizona @ Colorado | 8:10 PM | Coors Field |
| Pittsburgh @ SF Giants | 9:05 PM | Oracle Park |
| Minnesota @ LA Angels | 9:07 PM | Angel Stadium |
| Sun Aug 14 | Time | Location |
| San Diego @ Washington | 12:05 PM | Nationals Park |
| Cleveland @ Toronto | 1:37 PM | Rogers Centre |
| Baltimore @ Tampa Bay | 1:40 PM | Tropicana Field |
| Atlanta @ Miami | 1:40 PM | loanDepot Park |
| Chi Cubs @ Cincinnati | 1:40 PM | Great American Ball Park |
| Philadelphia @ NY Mets | 1:40 PM | Citi Field |
| Detroit @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| LA Dodgers @ Kansas City | 2:10 PM | Kauffman Stadium |
| Oakland @ Houston | 2:10 PM | Minute Maid Park |
| Milwaukee @ St. Louis | 2:15 PM | Busch Stadium |
| Seattle @ Texas | 2:35 PM | Globe Life Field |
| Arizona @ Colorado | 3:10 PM | Coors Field |
| Pittsburgh @ SF Giants | 4:05 PM | Oracle Park |
| Minnesota @ LA Angels | 4:07 PM | Angel Stadium |
| NY Yankees @ Boston | 7:08 PM | Fenway Park |
| Mon Aug 15 | Time | Location |
| Detroit @ Cleveland | 3:10 PM | Progressive Field |
| Detroit @ Cleveland | 6:10 PM | Progressive Field |
| San Diego @ Miami | 6:40 PM | loanDepot Park |
| Philadelphia @ Cincinnati | 6:40 PM | Great American Ball Park |
| Chi Cubs @ Washington | 7:05 PM | Nationals Park |
| Tampa Bay @ NY Yankees | 7:05 PM | Yankee Stadium |
| Baltimore @ Toronto | 7:07 PM | Rogers Centre |
| NY Mets @ Atlanta | 7:20 PM | Truist Park |
| Kansas City @ Minnesota | 7:40 PM | Target Field |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| LA Dodgers @ Milwaukee | 8:10 PM | American Family Field |
| Houston @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Seattle @ LA Angels | 9:38 PM | Angel Stadium |
| Arizona @ SF Giants | 9:45 PM | Oracle Park |
| Tue Aug 16 | Time | Location |
| San Diego @ Miami | 6:40 PM | loanDepot Park |
| Philadelphia @ Cincinnati | 6:40 PM | Great American Ball Park |
| Tampa Bay @ NY Yankees | 7:05 PM | Yankee Stadium |
| Chi Cubs @ Washington | 7:05 PM | Nationals Park |
| Boston @ Pittsburgh | 7:05 PM | PNC Park |
| Baltimore @ Toronto | 7:07 PM | Rogers Centre |
| Detroit @ Cleveland | 7:10 PM | Progressive Field |
| NY Mets @ Atlanta | 7:20 PM | Truist Park |
| Kansas City @ Minnesota | 7:40 PM | Target Field |
| Colorado @ St. Louis | 7:45 PM | Busch Stadium |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| Houston @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| LA Dodgers @ Milwaukee | 8:10 PM | American Family Field |
| Seattle @ LA Angels | 9:38 PM | Angel Stadium |
| Arizona @ SF Giants | 9:45 PM | Oracle Park |
| Wed Aug 17 | Time | Location |
| Philadelphia @ Cincinnati | 12:35 PM | Great American Ball Park |
| Chi Cubs @ Washington | 1:05 PM | Nationals Park |
| Kansas City @ Minnesota | 1:10 PM | Target Field |
| Baltimore @ Toronto | 3:07 PM | Rogers Centre |
| Seattle @ LA Angels | 4:07 PM | Angel Stadium |
| San Diego @ Miami | 4:10 PM | loanDepot Park |
| Boston @ Pittsburgh | 7:05 PM | PNC Park |
| Tampa Bay @ NY Yankees | 7:05 PM | Yankee Stadium |
| Detroit @ Cleveland | 7:10 PM | Progressive Field |
| NY Mets @ Atlanta | 7:20 PM | Truist Park |
| Colorado @ St. Louis | 7:45 PM | Busch Stadium |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| Houston @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| LA Dodgers @ Milwaukee | 8:10 PM | American Family Field |
| Arizona @ SF Giants | 9:45 PM | Oracle Park |
| Thu Aug 18 | Time | Location |
| Colorado @ St. Louis | 1:15 PM | Busch Stadium |
| Oakland @ Texas | 2:05 PM | Globe Life Field |
| Houston @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| LA Dodgers @ Milwaukee | 2:10 PM | American Family Field |
| Chi Cubs @ Baltimore | 3:05 PM | Oriole Park at Camden Yards |
| Arizona @ SF Giants | 3:45 PM | Oracle Park |
| Boston @ Pittsburgh | 7:05 PM | PNC Park |
| Toronto @ NY Yankees | 7:05 PM | Yankee Stadium |
| Kansas City @ Tampa Bay | 7:10 PM | Tropicana Field |
| NY Mets @ Atlanta | 7:20 PM | Truist Park |
| Washington @ San Diego | 9:40 PM | Petco Park |
| Fri Aug 19 | Time | Location |
| Milwaukee @ Chi Cubs | 2:20 PM | Wrigley Field |
| Boston @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Cincinnati @ Pittsburgh | 7:05 PM | PNC Park |
| NY Mets @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Toronto @ NY Yankees | 7:05 PM | Yankee Stadium |
| Kansas City @ Tampa Bay | 7:10 PM | Tropicana Field |
| Chi Sox @ Cleveland | 7:10 PM | Progressive Field |
| LA Angels @ Detroit | 7:10 PM | Comerica Park |
| Houston @ Atlanta | 7:20 PM | Truist Park |
| Texas @ Minnesota | 8:10 PM | Target Field |
| SF Giants @ Colorado | 8:40 PM | Coors Field |
| St. Louis @ Arizona | 9:40 PM | Chase Field |
| Washington @ San Diego | 9:40 PM | Petco Park |
| Seattle @ Oakland | 9:40 PM | RingCentral Coliseum |
| Miami @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sat Aug 20 | Time | Location |
| Toronto @ NY Yankees | 1:05 PM | Yankee Stadium |
| NY Mets @ Philadelphia | 1:05 PM | Citizens Bank Park |
| LA Angels @ Detroit | 1:10 PM | Comerica Park |
| Milwaukee @ Chi Cubs | 2:20 PM | Wrigley Field |
| Boston @ Baltimore | 4:05 PM | Oriole Park at Camden Yards |
| Kansas City @ Tampa Bay | 4:10 PM | Tropicana Field |
| Chi Sox @ Cleveland | 6:10 PM | Progressive Field |
| Cincinnati @ Pittsburgh | 7:05 PM | PNC Park |
| Texas @ Minnesota | 7:10 PM | Target Field |
| NY Mets @ Philadelphia | 7:15 PM | Citizens Bank Park |
| Houston @ Atlanta | 7:15 PM | Truist Park |
| Seattle @ Oakland | 7:15 PM | RingCentral Coliseum |
| SF Giants @ Colorado | 8:10 PM | Coors Field |
| St. Louis @ Arizona | 8:10 PM | Chase Field |
| Washington @ San Diego | 8:40 PM | Petco Park |
| Miami @ LA Dodgers | 9:10 PM | Dodger Stadium |
| Sun Aug 21 | Time | Location |
| Cincinnati @ Pittsburgh | 1:35 PM | PNC Park |
| NY Mets @ Philadelphia | 1:35 PM | Citizens Bank Park |
| Houston @ Atlanta | 1:35 PM | Truist Park |
| Toronto @ NY Yankees | 1:35 PM | Yankee Stadium |
| Kansas City @ Tampa Bay | 1:40 PM | Tropicana Field |
| LA Angels @ Detroit | 1:40 PM | Comerica Park |
| Texas @ Minnesota | 2:10 PM | Target Field |
| Milwaukee @ Chi Cubs | 2:20 PM | Wrigley Field |
| SF Giants @ Colorado | 3:10 PM | Coors Field |
| Seattle @ Oakland | 4:07 PM | RingCentral Coliseum |
| St. Louis @ Arizona | 4:10 PM | Chase Field |
| Miami @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Washington @ San Diego | 4:10 PM | Petco Park |
| Boston vs. Baltimore | 7:10 PM | BB&T Ballpark at HistoricBowman Field |
| Mon Aug 22 | Time | Location |
| Chi Sox @ Kansas City | 2:10 PM | Kauffman Stadium |
| NY Mets @ NY Yankees | 7:05 PM | Yankee Stadium |
| Cincinnati @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Atlanta @ Pittsburgh | 7:05 PM | PNC Park |
| LA Angels @ Tampa Bay | 7:10 PM | Tropicana Field |
| Texas @ Minnesota | 7:10 PM | Target Field |
| St. Louis @ Chi Cubs | 8:05 PM | Wrigley Field |
| Miami @ Oakland | 9:40 PM | RingCentral Coliseum |
| Milwaukee @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Tue Aug 23 | Time | Location |
| St. Louis @ Chi Cubs | 2:20 PM | Wrigley Field |
| Cincinnati @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Atlanta @ Pittsburgh | 7:05 PM | PNC Park |
| Chi Sox @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| NY Mets @ NY Yankees | 7:05 PM | Yankee Stadium |
| Toronto @ Boston | 7:10 PM | Fenway Park |
| SF Giants @ Detroit | 7:10 PM | Comerica Park |
| LA Angels @ Tampa Bay | 7:10 PM | Tropicana Field |
| St. Louis @ Chi Cubs | 8:05 PM | Wrigley Field |
| Minnesota @ Houston | 8:10 PM | Minute Maid Park |
| Arizona @ Kansas City | 8:10 PM | Kauffman Stadium |
| Texas @ Colorado | 8:40 PM | Coors Field |
| Miami @ Oakland | 9:40 PM | RingCentral Coliseum |
| Cleveland @ San Diego | 9:40 PM | Petco Park |
| Washington @ Seattle | 10:10 PM | T-Mobile Park |
| Milwaukee @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed Aug 24 | Time | Location |
| Atlanta @ Pittsburgh | 12:35 PM | PNC Park |
| SF Giants @ Detroit | 1:10 PM | Comerica Park |
| Texas @ Colorado | 3:10 PM | Coors Field |
| Miami @ Oakland | 3:37 PM | RingCentral Coliseum |
| Cleveland @ San Diego | 4:10 PM | Petco Park |
| Washington @ Seattle | 4:10 PM | T-Mobile Park |
| Chi Sox @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Cincinnati @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Toronto @ Boston | 7:10 PM | Fenway Park |
| LA Angels @ Tampa Bay | 7:10 PM | Tropicana Field |
| St. Louis @ Chi Cubs | 8:05 PM | Wrigley Field |
| Arizona @ Kansas City | 8:10 PM | Kauffman Stadium |
| Minnesota @ Houston | 8:10 PM | Minute Maid Park |
| Milwaukee @ LA Dodgers | 9:00 PM | Dodger Stadium |
| Thu Aug 25 | Time | Location |
| LA Angels @ Tampa Bay | 1:10 PM | Tropicana Field |
| St. Louis @ Chi Cubs | 2:20 PM | Wrigley Field |
| Cleveland @ Seattle | 4:10 PM | T-Mobile Park |
| Cincinnati @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Chi Sox @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Colorado @ NY Mets | 7:10 PM | Citi Field |
| Toronto @ Boston | 7:10 PM | Fenway Park |
| Minnesota @ Houston | 8:10 PM | Minute Maid Park |
| NY Yankees @ Oakland | 9:40 PM | RingCentral Coliseum |
| Fri Aug 26 | Time | Location |
| LA Dodgers @ Miami | 6:40 PM | loanDepot Park |
| Cincinnati @ Washington | 7:05 PM | Nationals Park |
| Pittsburgh @ Philadelphia | 7:05 PM | Citizens Bank Park |
| LA Angels @ Toronto | 7:07 PM | Rogers Centre |
| Colorado @ NY Mets | 7:10 PM | Citi Field |
| Tampa Bay @ Boston | 7:10 PM | Fenway Park |
| Detroit @ Texas | 8:05 PM | Globe Life Field |
| San Diego @ Kansas City | 8:10 PM | Kauffman Stadium |
| Arizona @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| SF Giants @ Minnesota | 8:10 PM | Target Field |
| Chi Cubs @ Milwaukee | 8:10 PM | American Family Field |
| Baltimore @ Houston | 8:10 PM | Minute Maid Park |
| Atlanta @ St. Louis | 8:15 PM | Busch Stadium |
| NY Yankees @ Oakland | 9:40 PM | RingCentral Coliseum |
| Cleveland @ Seattle | 10:10 PM | T-Mobile Park |
| Sat Aug 27 | Time | Location |
| LA Angels @ Toronto | 3:07 PM | Rogers Centre |
| Tampa Bay @ Boston | 4:10 PM | Fenway Park |
| Pittsburgh @ Philadelphia | 6:05 PM | Citizens Bank Park |
| LA Dodgers @ Miami | 6:10 PM | loanDepot Park |
| Detroit @ Texas | 7:05 PM | Globe Life Field |
| Cincinnati @ Washington | 7:05 PM | Nationals Park |
| Colorado @ NY Mets | 7:10 PM | Citi Field |
| San Diego @ Kansas City | 7:10 PM | Kauffman Stadium |
| Arizona @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| Chi Cubs @ Milwaukee | 7:10 PM | American Family Field |
| Baltimore @ Houston | 7:10 PM | Minute Maid Park |
| SF Giants @ Minnesota | 7:15 PM | Target Field |
| Atlanta @ St. Louis | 7:15 PM | Busch Stadium |
| NY Yankees @ Oakland | 9:07 PM | RingCentral Coliseum |
| Cleveland @ Seattle | 10:10 PM | T-Mobile Park |
| Sun Aug 28 | Time | Location |
| LA Dodgers @ Miami | 12:05 PM | loanDepot Park |
| Tampa Bay @ Boston | 1:35 PM | Fenway Park |
| Pittsburgh @ Philadelphia | 1:35 PM | Citizens Bank Park |
| Cincinnati @ Washington | 1:35 PM | Nationals Park |
| LA Angels @ Toronto | 1:37 PM | Rogers Centre |
| Colorado @ NY Mets | 1:40 PM | Citi Field |
| SF Giants @ Minnesota | 2:10 PM | Target Field |
| Chi Cubs @ Milwaukee | 2:10 PM | American Family Field |
| Baltimore @ Houston | 2:10 PM | Minute Maid Park |
| San Diego @ Kansas City | 2:10 PM | Kauffman Stadium |
| Arizona @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Detroit @ Texas | 2:35 PM | Globe Life Field |
| NY Yankees @ Oakland | 4:07 PM | RingCentral Coliseum |
| Cleveland @ Seattle | 4:10 PM | T-Mobile Park |
| Atlanta @ St. Louis | 7:08 PM | Busch Stadium |
| Mon Aug 29 | Time | Location |
| LA Dodgers @ Miami | 6:40 PM | loanDepot Park |
| St. Louis @ Cincinnati | 6:40 PM | Great American Ball Park |
| Chi Cubs @ Toronto | 7:07 PM | Rogers Centre |
| Boston @ Minnesota | 7:40 PM | Target Field |
| Pittsburgh @ Milwaukee | 8:10 PM | American Family Field |
| NY Yankees @ LA Angels | 9:38 PM | Angel Stadium |
| Philadelphia @ Arizona | 9:40 PM | Chase Field |
| San Diego @ SF Giants | 9:45 PM | Oracle Park |
| Tue Aug 30 | Time | Location |
| Baltimore @ Cleveland | 6:10 PM | Progressive Field |
| St. Louis @ Cincinnati | 6:40 PM | Great American Ball Park |
| Tampa Bay @ Miami | 6:40 PM | loanDepot Park |
| Oakland @ Washington | 7:05 PM | Nationals Park |
| Chi Cubs @ Toronto | 7:07 PM | Rogers Centre |
| Seattle @ Detroit | 7:10 PM | Comerica Park |
| LA Dodgers @ NY Mets | 7:10 PM | Citi Field |
| Colorado @ Atlanta | 7:20 PM | Truist Park |
| Boston @ Minnesota | 7:40 PM | Target Field |
| Houston @ Texas | 8:05 PM | Globe Life Field |
| Kansas City @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Pittsburgh @ Milwaukee | 8:10 PM | American Family Field |
| NY Yankees @ LA Angels | 9:38 PM | Angel Stadium |
| Philadelphia @ Arizona | 9:40 PM | Chase Field |
| San Diego @ SF Giants | 9:45 PM | Oracle Park |
| Wed Aug 31 | Time | Location |
| Houston @ Texas | 2:05 PM | Globe Life Field |
| Pittsburgh @ Milwaukee | 2:10 PM | American Family Field |
| San Diego @ SF Giants | 3:45 PM | Oracle Park |
| Baltimore @ Cleveland | 6:10 PM | Progressive Field |
| Tampa Bay @ Miami | 6:40 PM | loanDepot Park |
| St. Louis @ Cincinnati | 6:40 PM | Great American Ball Park |
| Oakland @ Washington | 7:05 PM | Nationals Park |
| Chi Cubs @ Toronto | 7:07 PM | Rogers Centre |
| Seattle @ Detroit | 7:10 PM | Comerica Park |
| LA Dodgers @ NY Mets | 7:10 PM | Citi Field |
| Colorado @ Atlanta | 7:20 PM | Truist Park |
| Boston @ Minnesota | 7:40 PM | Target Field |
| Kansas City @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| NY Yankees @ LA Angels | 9:38 PM | Angel Stadium |
| Philadelphia @ Arizona | 9:40 PM | Chase Field |
| Thu Sep 1 | Time | Location |
| Seattle @ Detroit | 1:10 PM | Comerica Park |
| Kansas City @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Oakland @ Washington | 4:05 PM | Nationals Park |
| LA Dodgers @ NY Mets | 4:10 PM | Citi Field |
| Baltimore @ Cleveland | 6:10 PM | Progressive Field |
| Texas @ Boston | 7:10 PM | Fenway Park |
| Colorado @ Atlanta | 7:20 PM | Truist Park |
| Milwaukee @ Arizona | 9:40 PM | Chase Field |
| Fri Sep 2 | Time | Location |
| Toronto @ Pittsburgh | 6:35 PM | PNC Park |
| Colorado @ Cincinnati | 6:40 PM | Great American Ball Park |
| Oakland @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Seattle @ Cleveland | 7:10 PM | Progressive Field |
| Texas @ Boston | 7:10 PM | Fenway Park |
| Kansas City @ Detroit | 7:10 PM | Comerica Park |
| Washington @ NY Mets | 7:10 PM | Citi Field |
| NY Yankees @ Tampa Bay | 7:10 PM | Tropicana Field |
| Miami @ Atlanta | 7:20 PM | Truist Park |
| Minnesota @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Chi Cubs @ St. Louis | 8:15 PM | Busch Stadium |
| Houston @ LA Angels | 9:38 PM | Angel Stadium |
| Milwaukee @ Arizona | 9:40 PM | Chase Field |
| San Diego @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Philadelphia @ SF Giants | 10:15 PM | Oracle Park |
| Sat Sep 3 | Time | Location |
| Philadelphia @ SF Giants | 4:05 PM | Oracle Park |
| Texas @ Boston | 4:10 PM | Fenway Park |
| Kansas City @ Detroit | 6:10 PM | Comerica Park |
| NY Yankees @ Tampa Bay | 6:10 PM | Tropicana Field |
| Toronto @ Pittsburgh | 6:35 PM | PNC Park |
| Oakland @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Washington @ NY Mets | 7:10 PM | Citi Field |
| Minnesota @ Chi Sox | 7:15 PM | Guaranteed Rate Field |
| Seattle @ Cleveland | 7:15 PM | Progressive Field |
| Chi Cubs @ St. Louis | 7:15 PM | Busch Stadium |
| Miami @ Atlanta | 7:20 PM | Truist Park |
| Milwaukee @ Arizona | 8:10 PM | Chase Field |
| Houston @ LA Angels | 9:07 PM | Angel Stadium |
| San Diego @ LA Dodgers | 9:10 PM | Dodger Stadium |
| Sun Sep 4 | Time | Location |
| Toronto @ Pittsburgh | 12:05 PM | PNC Park |
| Colorado @ Cincinnati | 12:10 PM | Great American Ball Park |
| Texas @ Boston | 1:35 PM | Fenway Park |
| Miami @ Atlanta | 1:35 PM | Truist Park |
| Oakland @ Baltimore | 1:35 PM | Oriole Park at Camden Yards |
| Kansas City @ Detroit | 1:40 PM | Comerica Park |
| Washington @ NY Mets | 1:40 PM | Citi Field |
| NY Yankees @ Tampa Bay | 1:40 PM | Tropicana Field |
| Minnesota @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Chi Cubs @ St. Louis | 2:15 PM | Busch Stadium |
| Seattle @ Cleveland | 2:40 PM | Progressive Field |
| Colorado @ Cincinnati | 3:10 PM | Great American Ball Park |
| Philadelphia @ SF Giants | 4:05 PM | Oracle Park |
| Houston @ LA Angels | 4:07 PM | Angel Stadium |
| Milwaukee @ Arizona | 4:10 PM | Chase Field |
| San Diego @ LA Dodgers | 7:08 PM | Dodger Stadium |
| Mon Sep 5 | Time | Location |
| Toronto @ Baltimore | 1:05 PM | Oriole Park at Camden Yards |
| Minnesota @ NY Yankees | 1:05 PM | Yankee Stadium |
| Toronto @ Baltimore | 4:05 PM | Oriole Park at Camden Yards |
| Milwaukee @ Colorado | 4:10 PM | Coors Field |
| Boston @ Tampa Bay | 4:10 PM | Tropicana Field |
| Washington @ St. Louis | 4:15 PM | Busch Stadium |
| Chi Sox @ Seattle | 6:40 PM | T-Mobile Park |
| Arizona @ San Diego | 6:40 PM | Petco Park |
| Texas @ Houston | 7:10 PM | Minute Maid Park |
| Cleveland @ Kansas City | 8:10 PM | Kauffman Stadium |
| Detroit @ LA Angels | 9:38 PM | Angel Stadium |
| SF Giants @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Tue Sep 6 | Time | Location |
| NY Mets @ Pittsburgh | 6:35 PM | PNC Park |
| Boston @ Tampa Bay | 6:40 PM | Tropicana Field |
| Miami @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Toronto @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Cincinnati @ Chi Cubs | 7:40 PM | Wrigley Field |
| Washington @ St. Louis | 7:45 PM | Busch Stadium |
| Cleveland @ Kansas City | 8:10 PM | Kauffman Stadium |
| Texas @ Houston | 8:10 PM | Minute Maid Park |
| Milwaukee @ Colorado | 8:40 PM | Coors Field |
| Detroit @ LA Angels | 9:38 PM | Angel Stadium |
| Arizona @ San Diego | 9:40 PM | Petco Park |
| Atlanta @ Oakland | 9:40 PM | RingCentral Coliseum |
| Chi Sox @ Seattle | 9:40 PM | T-Mobile Park |
| SF Giants @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed Sep 7 | Time | Location |
| NY Mets @ Pittsburgh | 12:35 PM | PNC Park |
| Minnesota @ NY Yankees | 3:05 PM | Yankee Stadium |
| Milwaukee @ Colorado | 3:10 PM | Coors Field |
| Atlanta @ Oakland | 3:37 PM | RingCentral Coliseum |
| Detroit @ LA Angels | 4:07 PM | Angel Stadium |
| SF Giants @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Chi Sox @ Seattle | 4:10 PM | T-Mobile Park |
| Minnesota @ NY Yankees | 6:05 PM | Yankee Stadium |
| NY Mets @ Pittsburgh | 6:35 PM | PNC Park |
| Boston @ Tampa Bay | 6:40 PM | Tropicana Field |
| Miami @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Toronto @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Cincinnati @ Chi Cubs | 7:40 PM | Wrigley Field |
| Washington @ St. Louis | 7:45 PM | Busch Stadium |
| Texas @ Houston | 8:10 PM | Minute Maid Park |
| Cleveland @ Kansas City | 8:10 PM | Kauffman Stadium |
| Arizona @ San Diego | 8:40 PM | Petco Park |
| Thu Sep 8 | Time | Location |
| Washington @ St. Louis | 1:15 PM | Busch Stadium |
| Cincinnati @ Chi Cubs | 2:20 PM | Wrigley Field |
| SF Giants @ Milwaukee | 4:10 PM | American Family Field |
| Miami @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Minnesota @ NY Yankees | 7:05 PM | Yankee Stadium |
| SF Giants @ Milwaukee | 7:10 PM | American Family Field |
| Chi Sox @ Oakland | 9:40 PM | RingCentral Coliseum |
| Fri Sep 9 | Time | Location |
| SF Giants @ Chi Cubs | 4:05 PM | Wrigley Field |
| St. Louis @ Pittsburgh | 6:35 PM | PNC Park |
| NY Mets @ Miami | 6:40 PM | loanDepot Park |
| Boston @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Tampa Bay @ NY Yankees | 7:05 PM | Yankee Stadium |
| Washington @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Toronto @ Texas | 8:05 PM | Globe Life Field |
| LA Angels @ Houston | 8:10 PM | Minute Maid Park |
| Detroit @ Kansas City | 8:10 PM | Kauffman Stadium |
| Cleveland @ Minnesota | 8:10 PM | Target Field |
| Cincinnati @ Milwaukee | 8:10 PM | American Family Field |
| Arizona @ Colorado | 8:40 PM | Coors Field |
| LA Dodgers @ San Diego | 9:40 PM | Petco Park |
| Atlanta @ Seattle | 9:40 PM | T-Mobile Park |
| Chi Sox @ Oakland | 9:40 PM | RingCentral Coliseum |
| Sat Sep 10 | Time | Location |
| Tampa Bay @ NY Yankees | 1:05 PM | Yankee Stadium |
| SF Giants @ Chi Cubs | 2:20 PM | Wrigley Field |
| Chi Sox @ Oakland | 4:07 PM | RingCentral Coliseum |
| Detroit @ Kansas City | 4:10 PM | Kauffman Stadium |
| Boston @ Baltimore | 5:05 PM | Oriole Park at Camden Yards |
| Washington @ Philadelphia | 6:05 PM | Citizens Bank Park |
| NY Mets @ Miami | 6:10 PM | loanDepot Park |
| Toronto @ Texas | 7:05 PM | Globe Life Field |
| Cleveland @ Minnesota | 7:15 PM | Target Field |
| Cincinnati @ Milwaukee | 7:15 PM | American Family Field |
| LA Angels @ Houston | 7:15 PM | Minute Maid Park |
| St. Louis @ Pittsburgh | 7:35 PM | PNC Park |
| Arizona @ Colorado | 8:10 PM | Coors Field |
| LA Dodgers @ San Diego | 8:40 PM | Petco Park |
| Atlanta @ Seattle | 9:10 PM | T-Mobile Park |
| Sun Sep 11 | Time | Location |
| Boston @ Baltimore | 1:05 PM | Oriole Park at Camden Yards |
| Washington @ Philadelphia | 1:05 PM | Citizens Bank Park |
| St. Louis @ Pittsburgh | 1:35 PM | PNC Park |
| Tampa Bay @ NY Yankees | 1:35 PM | Yankee Stadium |
| NY Mets @ Miami | 1:40 PM | loanDepot Park |
| Cleveland @ Minnesota | 2:10 PM | Target Field |
| Cincinnati @ Milwaukee | 2:10 PM | American Family Field |
| LA Angels @ Houston | 2:10 PM | Minute Maid Park |
| Detroit @ Kansas City | 2:10 PM | Kauffman Stadium |
| Toronto @ Texas | 2:35 PM | Globe Life Field |
| Arizona @ Colorado | 3:10 PM | Coors Field |
| Chi Sox @ Oakland | 4:07 PM | RingCentral Coliseum |
| LA Dodgers @ San Diego | 4:10 PM | Petco Park |
| Atlanta @ Seattle | 4:10 PM | T-Mobile Park |
| SF Giants @ Chi Cubs | 8:08 PM | Wrigley Field |
| Mon Sep 12 | Time | Location |
| Texas @ Miami | 1:10 PM | loanDepot Park |
| LA Angels @ Cleveland | 6:10 PM | Progressive Field |
| Houston @ Detroit | 6:40 PM | Comerica Park |
| Pittsburgh @ Cincinnati | 6:40 PM | Great American Ball Park |
| Tampa Bay @ Toronto | 7:07 PM | Rogers Centre |
| Chi Cubs @ NY Mets | 7:10 PM | Citi Field |
| Texas @ Miami | 7:10 PM | loanDepot Park |
| LA Dodgers @ Arizona | 9:40 PM | Chase Field |
| Atlanta @ SF Giants | 9:45 PM | Oracle Park |
| Tue Sep 13 | Time | Location |
| Pittsburgh @ Cincinnati | 12:35 PM | Great American Ball Park |
| Tampa Bay @ Toronto | 1:07 PM | Rogers Centre |
| LA Angels @ Cleveland | 6:10 PM | Progressive Field |
| Houston @ Detroit | 6:40 PM | Comerica Park |
| Philadelphia @ Miami | 6:40 PM | loanDepot Park |
| Pittsburgh @ Cincinnati | 6:40 PM | Great American Ball Park |
| Baltimore @ Washington | 7:05 PM | Nationals Park |
| Tampa Bay @ Toronto | 7:07 PM | Rogers Centre |
| Chi Cubs @ NY Mets | 7:10 PM | Citi Field |
| NY Yankees @ Boston | 7:10 PM | Fenway Park |
| Kansas City @ Minnesota | 7:40 PM | Target Field |
| Milwaukee @ St. Louis | 7:45 PM | Busch Stadium |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| Colorado @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| San Diego @ Seattle | 9:40 PM | T-Mobile Park |
| LA Dodgers @ Arizona | 9:40 PM | Chase Field |
| Atlanta @ SF Giants | 9:45 PM | Oracle Park |
| Wed Sep 14 | Time | Location |
| Pittsburgh @ Cincinnati | 12:35 PM | Great American Ball Park |
| LA Angels @ Cleveland | 1:10 PM | Progressive Field |
| Houston @ Detroit | 1:10 PM | Comerica Park |
| Colorado @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Atlanta @ SF Giants | 3:45 PM | Oracle Park |
| San Diego @ Seattle | 4:10 PM | T-Mobile Park |
| Philadelphia @ Miami | 6:40 PM | loanDepot Park |
| Baltimore @ Washington | 7:05 PM | Nationals Park |
| Tampa Bay @ Toronto | 7:07 PM | Rogers Centre |
| NY Yankees @ Boston | 7:10 PM | Fenway Park |
| Chi Cubs @ NY Mets | 7:10 PM | Citi Field |
| Kansas City @ Minnesota | 7:40 PM | Target Field |
| Milwaukee @ St. Louis | 7:45 PM | Busch Stadium |
| Oakland @ Texas | 8:05 PM | Globe Life Field |
| LA Dodgers @ Arizona | 9:40 PM | Chase Field |
| Thu Sep 15 | Time | Location |
| Chi Sox @ Cleveland | 1:10 PM | Progressive Field |
| Tampa Bay @ Toronto | 3:07 PM | Rogers Centre |
| Philadelphia @ Miami | 6:40 PM | loanDepot Park |
| Pittsburgh @ NY Mets | 7:20 PM | Citi Field |
| Oakland @ Houston | 7:20 PM | Minute Maid Park |
| Kansas City @ Minnesota | 7:40 PM | Target Field |
| Cincinnati @ St. Louis | 7:45 PM | Busch Stadium |
| San Diego @ Arizona | 9:40 PM | Chase Field |
| Fri Sep 16 | Time | Location |
| Colorado @ Chi Cubs | 2:20 PM | Wrigley Field |
| Miami @ Washington | 7:05 PM | Nationals Park |
| Baltimore @ Toronto | 7:07 PM | Rogers Centre |
| Minnesota @ Cleveland | 7:10 PM | Progressive Field |
| Texas @ Tampa Bay | 7:10 PM | Tropicana Field |
| Chi Sox @ Detroit | 7:10 PM | Comerica Park |
| Kansas City @ Boston | 7:10 PM | Fenway Park |
| Pittsburgh @ NY Mets | 7:10 PM | Citi Field |
| Philadelphia @ Atlanta | 7:20 PM | Truist Park |
| Oakland @ Houston | 8:10 PM | Minute Maid Park |
| NY Yankees @ Milwaukee | 8:10 PM | American Family Field |
| Cincinnati @ St. Louis | 8:15 PM | Busch Stadium |
| Seattle @ LA Angels | 9:38 PM | Angel Stadium |
| San Diego @ Arizona | 9:40 PM | Chase Field |
| LA Dodgers @ SF Giants | 10:15 PM | Oracle Park |
| Sat Sep 17 | Time | Location |
| Minnesota @ Cleveland | 1:10 PM | Progressive Field |
| Cincinnati @ St. Louis | 1:15 PM | Busch Stadium |
| Colorado @ Chi Cubs | 2:20 PM | Wrigley Field |
| Baltimore @ Toronto | 3:07 PM | Rogers Centre |
| Miami @ Washington | 4:05 PM | Nationals Park |
| Kansas City @ Boston | 4:10 PM | Fenway Park |
| Texas @ Tampa Bay | 6:10 PM | Tropicana Field |
| Chi Sox @ Detroit | 6:10 PM | Comerica Park |
| NY Yankees @ Milwaukee | 7:10 PM | American Family Field |
| Oakland @ Houston | 7:10 PM | Minute Maid Park |
| Pittsburgh @ NY Mets | 7:10 PM | Citi Field |
| Minnesota @ Cleveland | 7:10 PM | Progressive Field |
| Cincinnati @ St. Louis | 7:15 PM | Busch Stadium |
| Philadelphia @ Atlanta | 7:20 PM | Truist Park |
| San Diego @ Arizona | 8:10 PM | Chase Field |
| LA Dodgers @ SF Giants | 9:05 PM | Oracle Park |
| Seattle @ LA Angels | 9:07 PM | Angel Stadium |
| Sun Sep 18 | Time | Location |
| Chi Sox @ Detroit | 12:10 PM | Comerica Park |
| Texas @ Tampa Bay | 1:10 PM | Tropicana Field |
| Miami @ Washington | 1:35 PM | Nationals Park |
| Kansas City @ Boston | 1:35 PM | Fenway Park |
| Philadelphia @ Atlanta | 1:35 PM | Truist Park |
| Baltimore @ Toronto | 1:37 PM | Rogers Centre |
| Minnesota @ Cleveland | 1:40 PM | Progressive Field |
| Pittsburgh @ NY Mets | 1:40 PM | Citi Field |
| Oakland @ Houston | 2:10 PM | Minute Maid Park |
| NY Yankees @ Milwaukee | 2:10 PM | American Family Field |
| Cincinnati @ St. Louis | 2:15 PM | Busch Stadium |
| Colorado @ Chi Cubs | 2:20 PM | Wrigley Field |
| Seattle @ LA Angels | 4:07 PM | Angel Stadium |
| San Diego @ Arizona | 4:10 PM | Chase Field |
| LA Dodgers @ SF Giants | 7:08 PM | Oracle Park |
| Mon Sep 19 | Time | Location |
| Minnesota @ Cleveland | 1:10 PM | Progressive Field |
| Seattle @ LA Angels | 4:07 PM | Angel Stadium |
| Houston @ Tampa Bay | 6:40 PM | Tropicana Field |
| Chi Cubs @ Miami | 6:40 PM | loanDepot Park |
| Detroit @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Washington @ Atlanta | 7:20 PM | Truist Park |
| NY Mets @ Milwaukee | 7:40 PM | American Family Field |
| SF Giants @ Colorado | 8:40 PM | Coors Field |
| Arizona @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Tue Sep 20 | Time | Location |
| Arizona @ LA Dodgers | 3:10 PM | Dodger Stadium |
| Boston @ Cincinnati | 6:40 PM | Great American Ball Park |
| Houston @ Tampa Bay | 6:40 PM | Tropicana Field |
| Chi Cubs @ Miami | 6:40 PM | loanDepot Park |
| Toronto @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Pittsburgh @ NY Yankees | 7:05 PM | Yankee Stadium |
| Detroit @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Washington @ Atlanta | 7:20 PM | Truist Park |
| NY Mets @ Milwaukee | 7:40 PM | American Family Field |
| LA Angels @ Texas | 8:05 PM | Globe Life Field |
| Minnesota @ Kansas City | 8:10 PM | Kauffman Stadium |
| Cleveland @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| SF Giants @ Colorado | 8:40 PM | Coors Field |
| St. Louis @ San Diego | 9:40 PM | Petco Park |
| Seattle @ Oakland | 9:40 PM | RingCentral Coliseum |
| Arizona @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Wed Sep 21 | Time | Location |
| Washington @ Atlanta | 12:20 PM | Truist Park |
| NY Mets @ Milwaukee | 2:10 PM | American Family Field |
| Chi Cubs @ Miami | 6:40 PM | loanDepot Park |
| Boston @ Cincinnati | 6:40 PM | Great American Ball Park |
| Houston @ Tampa Bay | 6:40 PM | Tropicana Field |
| Toronto @ Philadelphia | 6:45 PM | Citizens Bank Park |
| Pittsburgh @ NY Yankees | 7:05 PM | Yankee Stadium |
| Detroit @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| LA Angels @ Texas | 8:05 PM | Globe Life Field |
| Minnesota @ Kansas City | 8:10 PM | Kauffman Stadium |
| Cleveland @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| SF Giants @ Colorado | 8:40 PM | Coors Field |
| St. Louis @ San Diego | 9:40 PM | Petco Park |
| Seattle @ Oakland | 9:40 PM | RingCentral Coliseum |
| Arizona @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Thu Sep 22 | Time | Location |
| LA Angels @ Texas | 2:05 PM | Globe Life Field |
| Minnesota @ Kansas City | 2:10 PM | Kauffman Stadium |
| SF Giants @ Colorado | 3:10 PM | Coors Field |
| Seattle @ Oakland | 3:37 PM | RingCentral Coliseum |
| St. Louis @ San Diego | 4:10 PM | Petco Park |
| Chi Cubs @ Pittsburgh | 6:35 PM | PNC Park |
| Toronto @ Tampa Bay | 6:40 PM | Tropicana Field |
| Milwaukee @ Cincinnati | 6:40 PM | Great American Ball Park |
| Houston @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Atlanta @ Philadelphia | 7:15 PM | Citizens Bank Park |
| Boston @ NY Yankees | 7:15 PM | Yankee Stadium |
| Cleveland @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| Arizona @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Fri Sep 23 | Time | Location |
| Chi Cubs @ Pittsburgh | 6:35 PM | PNC Park |
| Washington @ Miami | 6:40 PM | loanDepot Park |
| Milwaukee @ Cincinnati | 6:40 PM | Great American Ball Park |
| Boston @ NY Yankees | 7:05 PM | Yankee Stadium |
| Atlanta @ Philadelphia | 7:05 PM | Citizens Bank Park |
| Houston @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Toronto @ Tampa Bay | 7:10 PM | Tropicana Field |
| Cleveland @ Texas | 8:05 PM | Globe Life Field |
| Detroit @ Chi Sox | 8:10 PM | Guaranteed Rate Field |
| LA Angels @ Minnesota | 8:10 PM | Target Field |
| San Diego @ Colorado | 8:10 PM | Coors Field |
| Seattle @ Kansas City | 8:10 PM | Kauffman Stadium |
| SF Giants @ Arizona | 9:40 PM | Chase Field |
| NY Mets @ Oakland | 9:40 PM | RingCentral Coliseum |
| St. Louis @ LA Dodgers | 10:10 PM | Dodger Stadium |
| Sat Sep 24 | Time | Location |
| Boston @ NY Yankees | 1:05 PM | Yankee Stadium |
| Atlanta @ Philadelphia | 4:05 PM | Citizens Bank Park |
| NY Mets @ Oakland | 4:07 PM | RingCentral Coliseum |
| Washington @ Miami | 6:10 PM | loanDepot Park |
| Toronto @ Tampa Bay | 6:10 PM | Tropicana Field |
| Chi Cubs @ Pittsburgh | 6:35 PM | PNC Park |
| Milwaukee @ Cincinnati | 6:40 PM | Great American Ball Park |
| Houston @ Baltimore | 7:05 PM | Oriole Park at Camden Yards |
| Cleveland @ Texas | 7:05 PM | Globe Life Field |
| Detroit @ Chi Sox | 7:10 PM | Guaranteed Rate Field |
| Seattle @ Kansas City | 7:10 PM | Kauffman Stadium |
| LA Angels @ Minnesota | 7:10 PM | Target Field |
| SF Giants @ Arizona | 8:10 PM | Chase Field |
| San Diego @ Colorado | 8:10 PM | Coors Field |
| St. Louis @ LA Dodgers | 9:10 PM | Dodger Stadium |
| Sun Sep 25 | Time | Location |
| Houston @ Baltimore | 1:05 PM | Oriole Park at Camden Yards |
| Atlanta @ Philadelphia | 1:05 PM | Citizens Bank Park |
| Toronto @ Tampa Bay | 1:10 PM | Tropicana Field |
| Chi Cubs @ Pittsburgh | 1:35 PM | PNC Park |
| Milwaukee @ Cincinnati | 1:40 PM | Great American Ball Park |
| Washington @ Miami | 1:40 PM | loanDepot Park |
| LA Angels @ Minnesota | 2:10 PM | Target Field |
| Detroit @ Chi Sox | 2:10 PM | Guaranteed Rate Field |
| Seattle @ Kansas City | 2:10 PM | Kauffman Stadium |
| Cleveland @ Texas | 2:35 PM | Globe Life Field |
| San Diego @ Colorado | 3:10 PM | Coors Field |
| SF Giants @ Arizona | 3:40 PM | Chase Field |
| NY Mets @ Oakland | 4:07 PM | RingCentral Coliseum |
| St. Louis @ LA Dodgers | 4:10 PM | Dodger Stadium |
| Boston @ NY Yankees | 7:08 PM | Yankee Stadium |
| Mon Sep 26 | Time | Location |
| Cincinnati @ Pittsburgh | 6:35 PM | PNC Park |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| NY Yankees @ Toronto | 7:07 PM | Rogers Centre |
| Baltimore @ Boston | 7:10 PM | Fenway Park |
| Tue Sep 27 | Time | Location |
| Tampa Bay @ Cleveland | 6:10 PM | Progressive Field |
| Cincinnati @ Pittsburgh | 6:35 PM | PNC Park |
| Kansas City @ Detroit | 6:40 PM | Comerica Park |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| NY Yankees @ Toronto | 7:07 PM | Rogers Centre |
| Miami @ NY Mets | 7:10 PM | Citi Field |
| Baltimore @ Boston | 7:10 PM | Fenway Park |
| Philadelphia @ Chi Cubs | 7:40 PM | Wrigley Field |
| Chi Sox @ Minnesota | 7:40 PM | Target Field |
| St. Louis @ Milwaukee | 7:40 PM | American Family Field |
| Arizona @ Houston | 8:10 PM | Minute Maid Park |
| Oakland @ LA Angels | 9:38 PM | Angel Stadium |
| LA Dodgers @ San Diego | 9:40 PM | Petco Park |
| Texas @ Seattle | 9:40 PM | T-Mobile Park |
| Colorado @ SF Giants | 9:45 PM | Oracle Park |
| Wed Sep 28 | Time | Location |
| Cincinnati @ Pittsburgh | 12:35 PM | PNC Park |
| Tampa Bay @ Cleveland | 6:10 PM | Progressive Field |
| Kansas City @ Detroit | 6:40 PM | Comerica Park |
| Atlanta @ Washington | 7:05 PM | Nationals Park |
| NY Yankees @ Toronto | 7:07 PM | Rogers Centre |
| Baltimore @ Boston | 7:10 PM | Fenway Park |
| Miami @ NY Mets | 7:10 PM | Citi Field |
| Philadelphia @ Chi Cubs | 7:40 PM | Wrigley Field |
| Chi Sox @ Minnesota | 7:40 PM | Target Field |
| St. Louis @ Milwaukee | 7:40 PM | American Family Field |
| Arizona @ Houston | 8:10 PM | Minute Maid Park |
| Oakland @ LA Angels | 9:38 PM | Angel Stadium |
| Texas @ Seattle | 9:40 PM | T-Mobile Park |
| LA Dodgers @ San Diego | 9:40 PM | Petco Park |
| Colorado @ SF Giants | 9:45 PM | Oracle Park |
| Thu Sep 29 | Time | Location |
| Chi Sox @ Minnesota | 1:10 PM | Target Field |
| Kansas City @ Detroit | 1:10 PM | Comerica Park |
| Baltimore @ Boston | 1:35 PM | Fenway Park |
| Philadelphia @ Chi Cubs | 2:20 PM | Wrigley Field |
| Tampa Bay @ Cleveland | 6:10 PM | Progressive Field |
| Miami @ Milwaukee | 7:40 PM | American Family Field |
| Oakland @ LA Angels | 9:38 PM | Angel Stadium |
| LA Dodgers @ San Diego | 9:40 PM | Petco Park |
| Texas @ Seattle | 9:40 PM | T-Mobile Park |
| Colorado @ SF Giants | 9:45 PM | Oracle Park |
| Fri Sep 30 | Time | Location |
| Philadelphia @ Washington | 1:05 PM | Nationals Park |
| Cincinnati @ Chi Cubs |