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Louisville at SMU: Head to Head

Saturday Nov 22, 2025 12:00 pm - Dallas, TX
Odds: SMU by 3.5, Total Points: 50

Matchup Menu: LOU @ SMU

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Head To Head (Since 1995 Season)

These teams have met 2 times in the last 3 seasons (with 2025-2026 counting as one of those three). SMU has the better record at 2-0.

Below is their head-to-head history back through the 1995 season, not just over the past three seasons.

Date Winner Winner H/A/N Score ATS Cover O/U Result
11/22/25 SMU Home 38-6 SMU -3.5 Under 50.0
10/05/24 SMU Away 34-27 SMU +7.0 Over 54.5